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WAUKESHA, WI - GE Healthcare has received U.S. Food and Drug Administration (FDA) clearance for new breakthrough methods in ventilation monitoring that further expand the performance of the Engstrm Carestation ventilator. Developed with Professor Ola Stenqvist, M.D., Ph.D, anesthesiologist at Sahlgrenska University Hospital in Gothenburg, Sweden, SpiroDynamics and FRC INview are based on validated algorithms and measurements.1,2

The Engstrm Carestation, released in 2004, was the first critical care respiratory carestation to offer integration throughout the care process. The ventilator enables clinicians to integrate ventilation with monitoring modules capable of measuring advanced parameters.

With SpiroDynamics, critical care clinicians can now monitor tracheal pressure regardless of the ventilator setting. The breakthrough method facilitates compliance measurement at the beginning, middle and end of a breath for better assessment of overdistention, providing a dynostatic curve that better estimates Alveolar pressure. This further enhances detection of Intrinsic PEEP and inflection points.

FRC INview, a GE breakthrough technology, adds a new dimension to pulmonary monitoring by providing measurement of FRC without interrupting ventilation. It provides the ability to directly measure the end expiratory lung volume by slightly altering the delivered FiO2 level for short periods of time. Using the volumetric O2 and CO2 measurement capability of the Compact Airway module, the Engstrm Carestation displays the patient's FRC level through numeric values as well as a graphic curve.

"With the release of SpiroDynamics and FRC INview, GE Healthcare once again demonstrates our commitment to bringing real world, clinically-relevant solutions that impact the quality of patient care, by providing new information near-instantaneously at the point-of-care," said Paul Baumgart, general manager of GE Healthcare's Respiratory Care business.

SpiroDynamics is similar to Spirometry by creating a P/V loop that is analyzed by the user. As a component to the INview suite, SpiroDynamics provides a simple, reliable method to gather more accurate information on lung mechanics.

By providing a direct measurement of end expiratory lung volume on mechanically ventilated patients, FRC INview enables cycled, automatic measurement of FRC with no additional gas source required. Calculations are based on real-time lung function, without interruption of ventilation therapy and allows for a better assessment of the effectiveness of lung recruitment maneuvers.

"Although respiratory mechanics has been researched for many years, there has been a lack of measurement technology that allows clinical assessment of the tracheal and alveolar pressures in ventilated patients," said Dr. Stenqvist. "The SpiroDynamics and FRC INview extend the performance of the Engstrm Carestation by providing clinicians with pressure and volume measurements directly from the patient's lungs, plus the ability to measure their Functional Residual Capacity."

Both SpiroDynamics and FRC INview provide an improved view of the patient's respiratory function for enhanced patient ventilation support. When used together, the Engstrm Carestation combines the two technologies on-screen for a complete Lung INview display.

ABOUT GE HEALTHCARE
GE Healthcare provides transformational medical technologies and services that are shaping a new age of patient care. Our expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, performance improvement, drug discovery, and biopharmaceutical manufacturing technologies is helping clinicians around the world re-imagine new ways to predict, diagnose, inform and treat disease, so their patients can live their lives to the fullest. GE Healthcare's broad range of products and services enable healthcare providers to better diagnose and treat cancer, heart disease, neurological diseases, and other conditions earlier. Our vision for the future is to enable a new "early health" model of care focused on earlier diagnosis, pre-symptomatic disease detection and disease prevention.

Headquartered in the United Kingdom, GE Healthcare is a $15 billion unit of General Electric Company (NYSE: GE). Worldwide, GE Healthcare employs more than 43,000 people committed to serving healthcare professionals and their patients in more than 100 countries. For more information about GE Healthcare, visit our website at www.gehealthcare.com .

1. Senqvist O. "Practical Assessment of Respiratory Mechanics." British Journal of Anesthesiology. 2003; 91(1)92-105.
2. Sondergaard S., Houltz E., Lundin S., Stenqvist O. "Estimation of functional
residual capacity at the bedside using standard monitoring equipment: a modified nitrogen washout/washin technique requiring a small change of the inspired oxygen fraction." Anesth Analg. 2005 Jul;101(1):206-12.