SEARCH
Current Location:
>
> This Story


Log in or Register to rate this News Story
Forward Printable StoryPrint Comment

Never Miss a Story

Sign up for email alerts

 

More Industry Headlines

Pacemaker and ICD battery life needs to be extended to last 25 years Replacing batteries can lead to life-threatening infections

New telehealth legislation getting support from all angles CONNECT for Health Act gaining bipartisan, industry traction

Calling for a more personalized approach to preventing breast and ovarian cancers Psychological and medical risks need to be considered

Exposing the secrets of voodoo dolls through X-ray Virtual autopsy yields forensic insights in Haitian voodoo crimes

Portable seizure device yields unexpected mood benefits to PTSD patients Reduced sleeplessness, depression and nightmares by 30 percent

MR-compatible cardiac device implants add significant value to patient care A first-of-its-kind study finds value providers may be drawn to

Proton therapy is best for the most common pediatric brain tumor: study Medulloblastoma side effects diminished relative to conventional therapy

PET/CT beats CT and bone scans for detecting metastatic prostate cancer: study PET imaging of prostate has 'exploded' over last two years

Stryker to buy Sage for $2.8 billion HAI prevention product line expected to complement Stryker's offerings

Mathematical tool for MR may predict chance of migraines in concussion patients Shannon entropy may be more accurate than fractional anistropy

(Courtesy FDA)

Radiopharmaceutical cleared for breast and skin cancer

by Loren Bonner , DOTmed News Online Editor
On Wednesday, the U.S. Food and Drug Administration approved a new radioactive diagnostic imaging agent used to help doctors with the staging and management of breast and melanoma cancer patients.

According to Frederic H. Fahey, DSc, president of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), the new drug, technetium Tc 99m tilmanocept (Lymphoseek), will give doctors a more accurate way to find the sentinel lymph node, which in turn will help them determine where the patient's cancer has spread.

Story Continues Below Advertisement

We want to buy your Siemens Symphony or Avanto MRI -- today!

Top Dollar Paid, Fixed or Mobile. Call our Siemens Specialist for a Quote today -- 212-558-6600 Ext. 250 DOTmed Certified



During the standard sentinel node biopsy procedure for breast and melanoma cancer patients, which determines if the cancer has spread beyond the primary tumor and into the lymphatic system, doctors use a handheld radioactive detector to find which lymph nodes have been taken up by the agent's radioactivity. They remove them and look for cancer.

"Tc 99m tilmanocept lets you be more confident that you are taking the correct lymph node out," Fahey told DOTmed News.

Previous lymph node mapping agents — including sulfur colloid and isosulfan blue — were based on the size of the particle and would occasionally miss the correct sentinel lymph nodes. Sulfur colloid was approved by the FDA in 1974 and isosulfan blue in 1981.

Over 30 years later, the arrival of a new lymph node mapping agent — Lymphoseek — is a testament to the advancements in molecular imaging that have taken place over the past 10 to 15 years.

"It's a receptor-based agent that targets receptors on the surface of the lymphatic cells," said Fahey. "It has more of targeted approach to how it decides what the sentinel lymph node is."

In other words, whether the agent goes to the correct lymph node is no longer based on the size of the particle; instead it depends on the agent actually seeking out the lymphatic cells and sticking to them, according to Fahey.

For patients, this means the agent can be injected in a more convenient manner because it stays in place for a longer period of time.

"You can inject the agent on the day of the surgery or inject it the day before surgery," said Fahey.

According to a statement from the FDA, data from the clinical trials that established approval of the drug showed a notable number of nodes were localized only by Lymphoseek, compared with blue dye, another drug used to help locate lymph nodes.

The trials consisted of 332 patients in two trials with melanoma or breast cancer. All patients were injected with Lymphoseek and blue dye.

Lymphoseek is marketed by the Dublin, Ohio-based Navidea Biopharmaceuticals Inc., but will be distributed in the U.S. by Cardinal Health Inc., according to a statement from Navidea Biopharmaceuticals.

Back to DOTmed News
  Pages: 1

Related:


Interested in Medical Industry News? Subscribe to DOTmed's weekly news email and always be informed. Click here, it takes just 30 seconds.

You Must Be Logged In To Post A Comment

Advertise
Increase Your
Brand Awareness
Auctions + Private Sales
Get The
Best Price
Buy Equipment/Parts
Find The
Lowest Price
Daily News
Read The
Latest News
Directory
Browse All
DOTmed Users
Ethics on DOTmed
View Our
Ethics Program
Gold Parts Vendor Program
Receive PH
Requests
Gold Service Dealer Program
Receive RFP/PS
Requests
Healthcare Providers
See all
HCP Tools
Jobs/Training
Find/Fill
A Job
Parts Hunter +EasyPay
Get Parts
Quotes
Recently Certified
View Recently
Certified Users
Recently Rated
View Recently
Certified Users
Rental Central
Rent Equipment
For Less
Sell Equipment/Parts
Get The
Most Money
Service Technicians Forum
Find Help
And Advice
Simple RFP
Get Equipment
Quotes
Virtual Trade Show
Find Service
For Equipment
Access and use of this site is subject to the terms and conditions of our LEGAL NOTICE & PRIVACY NOTICE
Property of and Proprietary to DOTmed.com, Inc. Copyright ©2001-2016 DOTmed.com, Inc.
ALL RIGHTS RESERVED