Famed Beth Israel Hospital in New York City may soon close down, leaving Downtown Manhattanites on both the East and the West sides without a major hospital or emergency room.

Mt. Sinai Beth Israel nurses told The Villager newspaper last Tuesday, “They are going to make a big announcement before the end of the month ... We anticipate this is coming next week.”

The health care system is bleeding red ink, according to Crain's New York — $85.6 million in the first nine months of 2015, running at a pace to rival its 2014 $90.7 million loss.

The business news site also revealed details of an "urgent alert" email sent by the New York State Nurses Association to its members.

“We have been informed by management that they will be announcing the downsizing of Beth Israel within the next week or two. Their plan is to move units and individuals throughout the system,” NYSNA officials told members.

The news of the hospital's peril prompted a joint letter expressing "grave concern" to Mt. Sinai Health System president and CEO Kenneth Davis from shocked local politicians, including City Council members Daniel Garodnick, Rosie Mendez and Corey Johnson, Congress member Carolyn Maloney, Manhattan Borough President Gale Brewer, State Senator Brad Hoylman and Assembly members Brian Kavanagh and Richard Gottfried.

They advised Davis that "Beth Israel has been a constant presence and resource for the entire city, and the East Side of Manhattan in particular. Any downsizing or closure at Beth Israel threatens to further strain an already overburdened network of health care providers in Manhattan, reduce health care options and curtail services in the immediate neighborhood, and eliminate jobs."

In addition, their letter also warned that "the loss of the Beth Israel Neonatal Intensive Care Unit [NICU] is instructive – while Mount Sinai may have felt comfortable with closing the facility at Beth Israel because it has other NICUs in its system, this decision forces local parents to travel out of their area at a highly stressful and time-starved period in their lives."

The threat of shuttering the facility follows the closing of St. Vincent's Hospital in 2010. That facility, on the Lower West Side, had been on the front lines in the early fight against HIV/AIDs. It was replaced by an ultra-lux 200-unit Greenwich Lane condominium complex after proposals were made to build a new hospital nearby. This did not happen, according to the New York Times.

In 2015 a penthouse in the complex went for $21.1 million, according to the paper.

The politicians recalled the tragedy of the loss of St. Vincent's in their letter, stating, "we’ve seen this story before citywide, and Manhattan has suffered in particular with the shuttering of St. Vincent’s Hospital in Greenwich Village. After the closure of St. Vincent’s, hospitals across the borough experienced a sharp rise in visits."

Beth Israel is now the only large hospital in the Downtown area of Manhattan. Its leadership has proposed that a new hospital could be built nearby — similar to proposals concerning a replacement for St. Vincent's. “They [Mt. Sinai management] had said they were going to rebuild — and this is what we were told,” one of the sources told the Villager. “First, they said they were going to rebuild at the corner of 17th Street, where they own apartments. They said they were going to build by the New York Eye and Ear Infirmary — they also own that.”

The bottom line, sources claimed, is that the hospital is already downsizing. The NICU has been moved uptown. “They’re going to close [the hospital] in months,” one of the nurses told the paper. “They are taking the services that were thriving at Beth Israel and moving them uptown. They have cut doctors’ salaries here, and therefore pushed them out.”

The hospital system includes the Uptown Mt. Sinai location, as well as the Eye and Ear Infirmary, Mount Sinai St. Luke’s, Mount Sinai West (formerly Roosevelt Hospital), Mount Sinai Brooklyn (formerly Kings Highway Hospital), and Mount Sinai Queens.

Mayor de Blasio had made the hospital closing issue a major piece of his campaign when he ran for the city's top office. A dozen hospitals shuttered during former Mayor Bloomberg's reign.

“We’re not going to accept the arguments that because it’s a challenging situation, we’re not going to get involved,” de Blasio said while running, according to the paper. “Mayors are supposed to get involved — that’s what we’re here for. This is the moment when we need to turn the corner.”

The Mount Sinai Health System remains circumspect about the fate of its Downtown facility. “Mount Sinai is committed to serving the community and offering the highest level of patient care. Leadership is currently discussing various options to accomplish these goals,” its spokesperson said in a statement given the paper.