DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
SEARCH
Current Location:
>
> This Story


Log in or Register to rate this News Story
Forward Printable StoryPrint Comment

 

More Industry Headlines

Third-party medical equipment service: high stakes in the ongoing debate Checking in with the FDA's examination of third-party stakeholders

Cleveland Clinic, American Cancer Society dump Trump's Mar-A-Lago Mounting blowback from health care industry in wake of Virginia aftermath

INSIGHTEC's Exablate Neuro hits 1,000 patient mark System installed in 30 medical facilities worldwide

Medica to acquire Mayo Clinic Health Solutions May improve access for patients with complex conditions

Enterprise imaging will make up 27 percent of imaging IT market by 2021 PACS vendors ramp up enterprise solutions to compete against multi-vendor IT models

Stryker’s Serrato Pedicle Screw gets FDA nod Part of the Xia 3 Spinal System

Robotic-assisted transhiatal esophagectomy is safe and effective for certain patients But it's a complex procedure to perform

Machine learning algorithm may predict early-stage Alzheimer's disease Already used for cancer

Siemens Healthineers collaborates with Houston Methodist Hospital Will provide advanced angio, MR, CT, molecular imaging and ultrasound technology

Nationwide hosts IAMERS forum on QMS in advance of FDA report Stakeholders discuss ISO quality management systems

(Courtesy FDA)

Radiopharmaceutical cleared for breast and skin cancer

by Loren Bonner , DOTmed News Online Editor
On Wednesday, the U.S. Food and Drug Administration approved a new radioactive diagnostic imaging agent used to help doctors with the staging and management of breast and melanoma cancer patients.

According to Frederic H. Fahey, DSc, president of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), the new drug, technetium Tc 99m tilmanocept (Lymphoseek), will give doctors a more accurate way to find the sentinel lymph node, which in turn will help them determine where the patient's cancer has spread.

Story Continues Below Advertisement

Streamline Your Radiology Workflow with RamSoft's PowerServer RIS/PACS

The PowerServer RIS/PACS is a single database application, essential to reducing redundant work, limiting manual data entry, and increasing consistency throughout healthcare practices. Click to learn how it will help you improve patient care and more.



During the standard sentinel node biopsy procedure for breast and melanoma cancer patients, which determines if the cancer has spread beyond the primary tumor and into the lymphatic system, doctors use a handheld radioactive detector to find which lymph nodes have been taken up by the agent's radioactivity. They remove them and look for cancer.

"Tc 99m tilmanocept lets you be more confident that you are taking the correct lymph node out," Fahey told DOTmed News.

Previous lymph node mapping agents — including sulfur colloid and isosulfan blue — were based on the size of the particle and would occasionally miss the correct sentinel lymph nodes. Sulfur colloid was approved by the FDA in 1974 and isosulfan blue in 1981.

Over 30 years later, the arrival of a new lymph node mapping agent — Lymphoseek — is a testament to the advancements in molecular imaging that have taken place over the past 10 to 15 years.

"It's a receptor-based agent that targets receptors on the surface of the lymphatic cells," said Fahey. "It has more of targeted approach to how it decides what the sentinel lymph node is."

In other words, whether the agent goes to the correct lymph node is no longer based on the size of the particle; instead it depends on the agent actually seeking out the lymphatic cells and sticking to them, according to Fahey.

For patients, this means the agent can be injected in a more convenient manner because it stays in place for a longer period of time.

"You can inject the agent on the day of the surgery or inject it the day before surgery," said Fahey.

According to a statement from the FDA, data from the clinical trials that established approval of the drug showed a notable number of nodes were localized only by Lymphoseek, compared with blue dye, another drug used to help locate lymph nodes.

The trials consisted of 332 patients in two trials with melanoma or breast cancer. All patients were injected with Lymphoseek and blue dye.

Lymphoseek is marketed by the Dublin, Ohio-based Navidea Biopharmaceuticals Inc., but will be distributed in the U.S. by Cardinal Health Inc., according to a statement from Navidea Biopharmaceuticals.

Back to HCB News
  Pages: 1

Related:


You Must Be Logged In To Post A Comment

Advertise
Increase Your
Brand Awareness
Auctions + Private Sales
Get The
Best Price
Buy Equipment/Parts
Find The
Lowest Price
Daily News
Read The
Latest News
Directory
Browse All
DOTmed Users
Ethics on DOTmed
View Our
Ethics Program
Gold Parts Vendor Program
Receive PH
Requests
Gold Service Dealer Program
Receive RFP/PS
Requests
Healthcare Providers
See all
HCP Tools
Jobs/Training
Find/Fill
A Job
Parts Hunter +EasyPay
Get Parts
Quotes
Recently Certified
View Recently
Certified Users
Recently Rated
View Recently
Certified Users
Rental Central
Rent Equipment
For Less
Sell Equipment/Parts
Get The
Most Money
Service Technicians Forum
Find Help
And Advice
Simple RFP
Get Equipment
Quotes
Virtual Trade Show
Find Service
For Equipment
Access and use of this site is subject to the terms and conditions of our LEGAL NOTICE & PRIVACY NOTICE
Property of and Proprietary to DOTmed.com, Inc. Copyright ©2001-2017 DOTmed.com, Inc.
ALL RIGHTS RESERVED