Results showed that Pd/Pa had a significant linear correlation between Pd/Pa and FFR. In the prospective validation cohort, a Pd/Pa value of <0.90 demonstrated excellent diagnostic performance against FFR in identifying residual ischemia (FFR<0.80) with an area under curve 0.91 (sensitivity 76 percent and specificity 92 percent)

"We strongly believe that the best result of a PCI is not only a successful stent implantation but the demonstration that improved blood flow has been established and ischemia eliminated, the principal mechanism by which PCI improves symptoms and clinical outcomes in patients. The concept being functionally optimized revascularization," said lead author, Abdul Hakeem, MD, FSCAI, Rutgers Robert Wood Johnson Medical School in New Brunswick, NJ. "The results of our study provide clinicians with an accurate instrument to gauge the physiological success of PCI which is associated with reduced treatment times, decreased costs and potentially improved clinical outcomes. We believe that a hybrid approach using Pd/Pa generally and FFR in selected patients (those with Pd/Pa<0.90) post PCI will improve the functional and likely clinical outcomes of percutaneous interventions."


The authors call for physicians to routinely measure Pd/Pa after intervention to establish the physiological success of PCI.


About SCAI:
The Society for Cardiovascular Angiography and Interventions is a 5,000-member professional organization representing invasive and interventional cardiologists in approximately 75 nations. SCAI's mission is to promote excellence in invasive/interventional cardiovascular medicine through physician education and representation, and advancement of quality standards to enhance patient care.

Back to HCB News

Cardiology Homepage