Save the Date - Our next Clean Sweep Live Auction will be on Tuesday, September 26th at 9:30AM EST

DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
Current Location:
> This Story

Log in or Register to rate this News Story
Forward Printable StoryPrint Send us your Comments


More Industry Headlines

Radiology Partners to acquire Southwest Diagnostic Imaging Joining with SDI 'represents about a 25 percent increase' in RP's size

Study finds MR detects 98 percent of pregnancy-related breast cancers May also inform surgical management of disease

NuVasive releases LessRay software technology system in the U.S. Allows for lower dose while still retaining high image quality

FDA gives nod for Hitachi’s Supria True64 CT System Economy compact model system that consists of a premium image quality chain

Mevion submits MEVION S250i for premarket approval Features improved pencil beam scanning

Making the business case for compliance Multimillion-dollar noncompliance fines have become almost routine in American health care

Technology Advisor - Health advocate avatar A 'knowledge interface' to mediate between individuals and the world of medical information

Michigan appeals court case could test lay-ownership of MR facility laws Must imaging facilities be owned by doctors?

Philips introduces its CardioMD IV SPECT system at ASNC meeting Smaller footprint and lower cost of ownership

Purchasing Insights: Service contracts for a CT scanner Insights on one of a hospital's biggest service decisions

New drug delivery system
may transform eye cancer treatment

Experimental Silicone Cup: Breakthrough for Eye Disease Patients

by Lynn Shapiro , Writer
A new drug delivery system that uses a tiny silicone cup sealed to the outer surface of the eyeball may greatly improve the way doctors deliver medicine to people with eye diseases, says A. Linn Murphree, M.D., director of the Retinoblastoma Program in The Vision Center at Childrens Hospital, Los Angeles.

Dr. Murphree tells DOTmed News that the tiny cup isolates the medication targeted to the eye from being absorbed into the blood stream. This new delivery system is a safe and non-invasive way of delivering effective doses of medications to the interior of the eye over long periods of time, he says.

Story Continues Below Advertisement

New OEC 9800 LCD upgrade available! Call today: 800-400-7972

Easy install retrofit kit! Extend the life of your OEC system by upgrading the CRTs to dual 2MP LED displays mounted on an articulating arm. Priced competitively & optimized for do-it-yourself installation in under an hour.

Dr. Murphree is especially interested in kids who have an eye cancer called retinoblastoma but he says the cup can be used to deliver drugs for any disease, including macular degeneration, glaucoma and diabetes.

Eye Drops Ineffective

Currently, the drops used for retinoblastoma and the injections used for macular degeneration are risky and ineffective, he says.

"When we give injections, it's like taking a whole bucket of water and throwing it at a building. We're splashing medicine on the eye, except most of it is running off. He adds that eye drops are just as ineffective, because while most diseases that affect vision are in the back portion of the eye, eye drops can only reach the front of the eye. "Traditionally, we've always had a real problem getting enough medicine inside the eye. So, now we inject medicine into a vein in the eye, but that requires a lot of drug therapy and a lot of side effects," Dr. Murphree says.

Macular degeneration is a case in point. Macular degeneration medicine must be injected into the eye once a month. Shots in the eye can lead to hemorrhaging, retinal detachment, and infections, he says.

"In the past, there was no way of isolating the drug while it slowly diffused into the eye. But the cup isolates the drug from being carried away by the blood vessels around the eye, using a soft silicone that's sealed to the outside of the eye, Dr. Murphree explains.

He says that the silicone cup is first sealed to the eye and is then injected with liquid medication to treat the disease. The cup releases medicine slowly over days or weeks.

Retinoblastoma: Dr. Murphree's Passion

Dr. Murphree is passionate about helping children beat retinoblastoma. Currently, he says, the only way to treat this disease is to inject chemotherapy medication into an eye vein and hope it reaches the cancer cells in one or perhaps both eyes.

"We are giving 99 percent more chemo than is needed to make sure the medicine gets into the eye, but most of it is going into the bloodstream, causing nausea, reducing kids' white cell count, and depressing their immune systems," he says. "Because the drug delivered via the cup is being administered directly into the eye and not systemically, you're not giving more than you need, and you're getting 30 to 40 times more of the drug delivered to the cancer site than with an injection."
  Pages: 1 - 2 >>


Increase Your
Brand Awareness
Auctions + Private Sales
Get The
Best Price
Buy Equipment/Parts
Find The
Lowest Price
Daily News
Read The
Latest News
Browse All
DOTmed Users
Ethics on DOTmed
View Our
Ethics Program
Gold Parts Vendor Program
Receive PH
Gold Service Dealer Program
Receive RFP/PS
Healthcare Providers
See all
HCP Tools
A Job
Parts Hunter +EasyPay
Get Parts
Recently Certified
View Recently
Certified Users
Recently Rated
View Recently
Certified Users
Rental Central
Rent Equipment
For Less
Sell Equipment/Parts
Get The
Most Money
Service Technicians Forum
Find Help
And Advice
Simple RFP
Get Equipment
Virtual Trade Show
Find Service
For Equipment
Access and use of this site is subject to the terms and conditions of our LEGAL NOTICE & PRIVACY NOTICE
Property of and Proprietary to DOTmed.com, Inc. Copyright ©2001-2017 DOTmed.com, Inc.