by
Barbara Kram, Editor | February 14, 2006
ABOUT THE INTERCEPT BLOOD SYSTEM
The INTERCEPT Blood System is designed to reduce the risk of transfusion-transmitted diseases by inactivating certain pathogens that may be present in donated blood components.

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The INTERCEPT Blood System is approved for use in Europe for platelets, and has been implemented by blood centers in several European countries. A CE mark application has been filed for the INTERCEPT Blood System for plasma and three Phase III trials in the United States have been completed. Phase III trials of the INTERCEPT Blood System for red blood cells were halted in 2003 after antibody reactivity was observed in two patients. Based on the development of a modified process that may diminish the likelihood of antibody reactivity with treated red cells, re-entry into clinical trials is planned.
ABOUT CERUS
Cerus Corporation is developing novel products for cancer, infectious disease and blood safety based on multiple, innovative technology platforms. The company is building a pipeline of next generation cancer immunotherapies by combining its proprietary attenuated Listeria vector platform with promising disease antigens. These products are designed to stimulate innate and T cell immune pathways, generating highly potent anti-tumor responses. The company's KBMA vaccine technology has potential broad applications against multiple pathogens. Cerus is applying its Helinx technology to develop the INTERCEPT Blood System, which is designed to enhance the safety of blood components through pathogen inactivation. The company's strategy is to leverage the broad potential of its technologies and products both on its own and through alliances. Cerus' collaborators include MedImmune and investigators at The Johns Hopkins University for cancer immunotherapy and BioOne for the INTERCEPT Blood System.
ABOUT BAXTER
Baxter International Inc., through its subsidiaries, assists health-care professionals and their patients with the treatment of complex medical conditions, including cancer, hemophilia, immune disorders, kidney disease and trauma. The company applies its expertise in medical devices, pharmaceuticals and biotechnology to make a meaningful difference in patients' lives.
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