The potential advantages of the X-Port device include a simple user interface, the ability to place it through the same introducer sheath used for the interventional procedure for greater convenience and speed, scalability, and lower cost of goods. In addition, X-Port is designed to be less invasive with a minimal amount of foreign material placed in the vessel wall. Cardica is now conducting preclinical studies to assess safety and preliminary efficacy of the X-Port device.

About Cook Incorporated
The world's largest privately held manufacturer of medical devices with international headquarters in Bloomington, Ind., Cook© Group Inc. (www.cookgroup.com) is a leading designer, manufacturer and global distributor of minimally invasive medical device technology for diagnostic and therapeutic procedures. Since its founding in 1963, Cook has created innovative technologies for stents and stent-grafts, catheters, wire guides, introducer needles and sheaths, embolization coils, medical biomaterials, vena cava filters, implanted cardiac lead extraction equipment and other minimally invasive medical devices.
About Cardica, Inc.
Cardica designs and manufactures automated anastomotic systems for coronary artery bypass graft (CABG) surgery. By replacing hand-sewn sutures with easy-to-use automated systems, Cardica provides cardiovascular surgeons with rapid, reliable and consistently reproducible anastomoses, or connections of blood vessels, the most critical aspect of the CABG procedure.

The C-Port© system, a distal anastomosis system, is marketed in Europe and received 510(K) clearance from the U.S. Food and Drug Administration in November 2005. The PAS-Port© system, a proximal anastomosis system, is marketed in Europe and Japan. Cardica also is developing additional devices to facilitate vascular and other surgical procedures. Go to www.cardica.com for more information.

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