ADx has the potential to confirm an Alzheimer’s diagnosis, as well as to rule out such a diagnosis. Misdiagnosed dementia patients not only receive the wrong therapies, but the cost of treating a misdiagnosed patient adds as much as $14,000 to the annual cost of treatment.

Related information: http://www.alz.org/facts/overview.asp


Powerful Technology

Alzeca’s innovative biodiagnostic platform is a nanoparticle that can encapsulate an imaging marker or other “payload” and pass through the normally impenetrable blood-brain barrier. The outside of each nanoparticle is designed to bind precisely to specific target substances in the brain, delivering the payload to that target.

ADx is the first product based on the platform. ADx carries an MR imaging agent as its payload and targets the amyloid plaques that are the hallmark of the onset of Alzheimer’s disease, developing ten or more years before cognitive impairment. Once ADx is bound to the plaques, they can be imaged in high resolution using a standard MRI scan. Related information: http://www.alzeca.com/technology

Superior Modalities

MR scans are far less costly and far more readily available throughout the world than the only current alternative, a PET scan. PET scans also require the use of radioactive imaging agents that preclude routine use, while ADx would permit physicians to track the patient’s condition.

Building Strong, Experienced Leadership and Scientific Expertise

Based on the progress, Alzeca has assembled a world class team of senior executives, including:

Scott W. Atlas, M.D., Chairman of the Board (former Chief of Neuroradiology at Stanford University Medical Center)
Carlo Medici, Chief Executive Officer (former CEO of Bracco Diagnostics, a global leader in imaging agents)
Thomas Hale, Chief Operating Officer (20 years with Abbott Laboratories and 10 years of additional experience in drug development)
“Alzeca has brought together incredible breakthrough science and a highly experienced leadership team to accelerate the company’s strategy and address a huge unmet need for physicians and patients alike in neurodegenerative disease,” said Scott W. Atlas, M.D., Chairman. “We must greatly improve the standard of care as 98 percent of new treatments fail to be FDA-approved. Earlier detection of Alzheimer’s disease can help patients and their families make better life decisions.”

Direct link to leadership team page: http://www.alzeca.com/leadershipteam

Alzeca Biosciences was founded on technology invented at the University of Texas-Houston, and is based in Houston. The company was formed specifically to develop the immense potential of ADx and its underlying technology platform. Alzeca’s leadership team includes world-renowned experts in diagnostic imaging innovation, clinical neuroscience, and commercial biotech development.

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