"Black women in all categories, including the most common breast cancers, were likely to have a worse prognosis," Olopade said.
"Understanding the basic, underlying genetic differences between black and white women, the higher risk scores and the increased risk of recurrence should lead us to alternative treatment strategies," said Perou.
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The crucial long-term benefit of this study, according to Olopade, is that "it is a step toward the development of polygenic biomarkers, tools that can help us better understand each patient's prognosis and, as we learn more, play a role in choosing the best treatment."
"Genes matter," she added. "This is a foot in the door for precision medicine, for scientifically targeted treatment."
"This study now outlines a path for us to personalize breast cancer risk assessment and develop better strategies to empower all women, especially black women, to know their genetics and be more proactive in managing their risk," Perou said.
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