by
Thomas Dworetzky, Contributing Reporter | June 19, 2017
They found that tau PET could not only improve diagnostics, but also might be used in the development of new drugs to treat Alzheimer’s.
To underscore the possible usefulness of tau, researchers at Washington University School of Medicine were reported in May, 2016, to have used a tau-protein-binding imaging agent, and found that measures of tau are
better indicators of cognitive decline associated with Alzheimer's than amyloid beta measurements.
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In the study, which appeared in Science Translational Medicine, the lead author, Dr. Beau M. Ances, reported that the analysis helps them to establish that the new tau agent, T807, is an important tool for understanding the timeline of Alzheimer's progression and for uncovering the regions of the brain that are involved.
"It's a location, location, location kind of business," said Ances, the Associated Press reported at the time, "The plaque starts setting up the situation, and tau is almost the executioner."
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