Dr. O'Connell has focused on drug therapy for the older population with an emphasis on prevention and treatment of osteoporosis. She is the course director of the Special Patient Populations module that includes women's health. Dr. O'Connell is the Past President of the American College of Clinical Pharmacy, a clinical pharmacist and PharmD student preceptor at the Detroit Medical Center Geriatric Center of Excellence.
Named a "Local Legend" by the American Women's Medical Association and the NIH as part of the "Changing the Face of Medicine" project, Dr. O'Connor is active in research and education. She has published leading research on saving limbs after treatment for pelvic and shoulder cancers. Dr. O'Connor was the first female member of both the Musculoskeletal Tumor Society (MSTS) and the American Association of Hip and Knee Surgeons (AAHKS). She is Chair of the Department of Orthopedic Surgery at the Mayo Clinic in Jacksonville, Florida, Dr. O'Connor is currently President of the Ruth Jackson Orthopedic Society and Chair of the American Academy of Orthopaedic Surgeons' Women's Health Issues Advisory Board.

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As Director for the Center for Women's Health Research, Leadership and Advocacy, Temple University, Dr. Rosen helped initiate the Center in 2005 and has developed multidisciplinary and interdisciplinary collaborations to foster excellence in women's health research and support the mentored research career development of junior faculty at Temple University. Dr. Rosen was recently named the first ELAM (Executive Leadership in Academic Medicine) Senior Scholar, a position created to help advance research and other initiatives aimed at addressing the lack of women leaders at the upper levels of U.S. academic health centers.
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