“These studies emphasize the potential importance of individualizing therapies for specific tumor characteristics, and the need to develop ways to identify these characteristics with either biopsies or noninvasive imaging approaches,” Yeh said.

In addition to Yeh and Collisson, other authors on the first study were Robert J. Torphy, a former medical student at the University of North Carolina School of Medicine, and now of the University of Colorado in Aurora; Zhen Wang, Aisha True-Yasaki, and Benjamin Yeh of UCSF, Keith E. Volmar of Rex Healthcare, and Naim Rashid of UNC-Chapel Hill, Julia Johansen of the University of Copenhagen, and Michael A. Hollingsworth of the University of Nebraska.


Other authors on the second study included K.L. Aung, A. Dodd, S. Creighton, S. Moura, and M.J. Moore of the Princess Margaret Cancer Centre; S.E. Fischer, B. Southwood, S.B. Liang, D. Chadwick, G.M. O’Kane, H.A.A. Albaba, and S. Ghai, of the University Health Network; G.H. Jang, A. Zhang, R.C. Grant, A.A. Connor, and F. Notta, of the PanCuRx Translational Research Institute; R.E. Denroche, J.K. Miller, F. Mbabaali, D. Pasternack, I.M. Lungu, J.M.S. Bartlett, M. Lemire, L. Timms, P.M. Krzyzanowski, and J.M. Wilson of the Ontario Institute for Cancer Research; S. Holter and S. Gallinger of Mount Sinai Hospital; R.A. Moffitt, a former postdoctoral fellow at UNC Lineberger and now of Stony Brook University; N.C. Dhani, D.W. Hedley, and J.J. Knox of Princess Margaret Hospital.

The study on pancreatic stroma density was funded by the National Institutes of Health, the University Cancer Research Fund, the University of California, San Francisco Resource Allocation Program Funding, and the Doris Duke Charitable Foundation.

The study led from the Princess Margaret Cancer Centre was conducted with support from the National Institutes of Health and the Ontario Institute for Cancer Research (PanCuRx Translational Research Initiative through funding from the Government of Ontario.

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