Cardiac resynchronization therapy offers a proven treatment for heart failure, but as many as 30 percent of heart failure patients receiving conventional CRT do not respond to the treatment. Without CRT, people with heart failure deteriorate and may eventually die of the condition. For many, medicine only helps to a limited degree.
“We believe SOLVE-CRT to be a landmark study that will build on previous positive results of this first-of-its-kind innovation for heart failure patients,” said Allan Will, chairman and CEO of EBR Systems. “We are thrilled to have the participation and enthusiasm from so many world-class sites, who are motivated to expand the benefits of CRT therapy to patients who currently have no promising therapeutic alternatives.”
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Results of SELECT-LV, a multicenter European prospective trial involving 39 patients in six hospital centers, demonstrated sustained cardiovascular improvement for complex CRT patients treated with the WiSE CRT System, with the majority of patients experiencing persistent clinical benefits at six months. Clinical benefits included patient freedom from mortality and heart failure hospitalizations and improvement in quality of life and functional capacity.1
The WiSE™ CRT System received European CE Mark approval for its second-generation wireless transmitter and has enabled treatment for many patients who had previously failed treatment with conventional CRT devices.
About Heart Failure and Cardiac Resynchronization Therapy (CRT)
Heart failure is a serious condition in which the heart is unable to pump enough blood to meet the body’s demands. A progressive, debilitating disease, heart failure often occurs when electrical signals within the heart are disrupted, causing the heart’s ventricles to beat in an uncoordinated or unsynchronized pattern, which in turn enlarges the left ventricle and makes the heart less efficient.
Without therapy, people with heart failure deteriorate and may eventually die of the condition. Cardiac resynchronization therapy offers a proven treatment that improves symptoms and reduces hospitalizations and mortality2,3 by electrically stimulating the heart. Also referred to as biventricular pacing, CRT uses wire leads to synchronize the left and the right ventricles so that the two chambers beat together, thereby improving the heart’s efficiency. Approximately 200,000 patients are treated worldwide each year with traditional CRT and about 155,000 of them are in the U.S.4
