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Molecular Imaging Homepage

Louisiana getting $14 million Center for Molecular Imaging and Therapy Increasing research opportunities, collaboration and radiopharmaceuticals

DOE transfers land to Coquí Pharma for isotope production facility Will be used primarily to produce Mo-99

PET uncovers abnormal tau deposits associated with CTE in live subjects May enable diagnosis of CTE in living people one day

Amyloid PET scans help with Alzheimer's clinical management New insights from the 11,000 patient IDEAS study

United Imaging's total-body PET scanner shows promise in four new studies Faster scans, lower dose and 'a level of detail never seen in PET'

NorthStar buys IBA electron accelerators for Mo-99 production Will increase production capacity and efficiencies

RadioMedix and Vect-Horus to develop brain theranostic agent for brain cancer Provide diagnosis and treatment of Glioblastoma Multiforme (GBM)

NIH awards $1.8 million to Magnetic Insight for neurovascular MPI Detects magnetic nanoparticle tracers, enables deep-tissue imaging

DOE to cut Moly-99 deals with four US firms Could be as much as $15 million per company, with partners matching awarded amounts

Women's brains appear three years younger than men's at the same age: PET study A machine-learning algorithm assisted with the analysis

A new role for PET in interventional procedures

From the June 2018 issue of DOTmed HealthCare Business News magazine

This portable PET scanner is novel in its form and function, and will unleash the power of PET imaging in therapy settings (surgery, radiation, and ablation therapy). It will transform PET from a diagnostic system to a theranostic one (theranostics, meaning therapeutic and diagnostic at once) that can be used at the point-of-care. It will bring urgently needed physiologic imaging to other interventions such as percutaneous thermal ablation and Y-90 embolization.

Catheter-based intra-myocardial delivery of therapeutics such as stem cells, anti-inflammatory agents, and genetic material is being explored for the treatment of heart disease. Current technologies rely on electrical or anatomical features to guide delivery to specific locations in the heart (e.g. fluoroscopy, electromechanical mapping). Molecular signals from PET radiotracers provide functional information that may be useful in guiding intra-myocardial therapeutic delivery. A PET scanner in an intervention room may identify injured myocardium via endocardial detection of IV-delivered PET radiotracers in real-time PET images, as well as intra-ventricular radiation detectors, and guide delivery of therapeutics to injured tissue via direct intra-myocardial injections.
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Farhad Daghighian
With portable imaging in the operating room or a catheterization laboratory come many new theranostic procedures never imagined before. Clinical demand is moving rapidly, and requires a reconfiguration of technology in which nuclear tracers are used to guide treatment in real time. By reconfiguring PET-design we are afforded new windows into the future of patient theranostics never achieved before in medicine.

About the author: Farhad Daghighian, PhD is president and chief scientist at Prescient Imaging, LLC

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