Under IRB approval, the RAPID platform was also used to select patients for two landmark stroke trials published in The New England Journal of Medicine, DAWN and DEFUSE 3, that successfully treated patients up to twenty-four hours after onset. RAPID was the exclusive imaging tool used to aid in patient selection in both studies. The results of the studies helped change the American Heart Association and American Stroke Association’s stroke guidelines to include CT perfusion and MR perfusion.
The prior treatment window for mechanical thrombectomy was up to six hours. Starting in 2018, select patients with salvageable brain tissue identified through advanced imaging are now eligible for treatment up to twenty-four hours after they were last seen well.
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About iSchemaView
iSchemaView is the worldwide leader in advanced imaging for stroke. Installed in over 700 hospitals and stroke centers, iSchemaView’s RAPID (automated CTP, MR, CTA and ASPECTS) is the most advanced stroke imaging platform. In clinical trials, under IRB, RAPID has been shown to aid in the selection of patients in early- and late-window stroke trials, including SWIFT PRIME, EXTEND IA, DAWN, DEFUSE 3 and EXTEND. In addition to achieving the best clinical outcomes and largest treatment effects ever obtained, these landmark studies led to new American Heart Association and American Stroke Association guidelines and have dramatically altered the management of acute stroke around the world.
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