"These results are very promising," Dr. Drukker said. "Combining 3CB image analysis with mammography radiomics, the reduction in recalls was substantial."
Dr. Drukker said the combined 3CB-radiomics approach has the potential to play an increasingly prominent role in breast cancer diagnosis and perhaps also screening. She noted that 3CB can easily be added to mammography without requiring extensive modifications of existing equipment.
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"The patient is already getting the mammography, plus we get all this extra information with only a 10 percent additional dose of radiation," she said.
This approach is still experimental at this stage, and further work is needed to make it available to patients. The researchers plan to study how the combined approach will help radiologists make their final determinations. They also want to study the approach using digital breast tomosynthesis, sometimes called "3D" mammography, which reduces the problem of overlapping breast tissue inherent to regular mammography. A tumor's unique water-lipid-protein signature might be even clearer with tomosynthesis, Dr. Drukker said.
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