These findings offer evidence that breast-conserving treatment is feasible and effective through a second lumpectomy and 3D-CRT partial breast reirradiation, providing a viable substitute for mastectomy.

In addition to Arthur, this study was co-authored by Laurie Cuttino, M.D., and Dorin A. Todor, Ph.D., of VCU Massey Cancer Center; Kathryn A. Winter, M.S., and Jennifer Moughan, M.S., of NRG Oncology Statistics and Data Management Center; Wendy A. Woodward, M.D., and Henry M. Kuerer, M.D., Ph.D., of the University of Texas MD Anderson Cancer Center; Bruce Haffty, M.D., of Rutgers Cancer Institute of New Jersey; Pramila Rani Anne, M.D., of Thomas Jefferson University Hospital; Penny Anderson, M.D., of Fox Chase Cancer Center; Beryl McCormick, M.D., of Memorial Sloan Kettering Cancer Center; Sally Cheston, M.D., of the University of Maryland/Greenebaum Cancer Center; Walter M. Sahijdak, M.D., of Michigan Cancer Research Consortium; Daniel Canaday, M.D., of Cape Cod Hospital; Doris R. Brown, M.D., Ph.D., of Wake Forest University Health Sciences; Adam Currey, M.D., of Froedtert and the Medical College of Wisconsin; Christine M. Fisher, M.D., M.P.H., of the University of Colorado Hospital; Reshma Jagsi, M.D., D.Phil., of the University of Michigan Comprehensive Cancer Center and Julia R. White, M.D., of Ohio State University Comprehensive Cancer Center.


The study was supported by awards from the National Cancer Institute (UG1CA189867 and U24CA180803) and NRG Oncology (U10CA180868, U10CA180822 and U24CA196067) and, in part, with funding from Massey's NIH-NCI Cancer Center Support Grant P30 CA016059.

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