"The PET scans revealed an increased number of AMPA receptors in epileptic lesions in the brains of patients," says Takahashi.
Takahashi and his colleagues say the findings suggest that PET imaging with [11C]K-2 could provide an additional non-invasive technique for identifying epileptogenic foci in human brains, as current approaches have their limitations. This could help doctors better identify patients who are eligible for surgical removal of these foci.
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It could also help scientists re-categorize psychiatric disorders based on greater insight into the distribution of AMPA receptors.
The research team is currently conducting a clinical trial using the [11C]K-2 PET tracer with the aim of obtaining Japanese regulatory approval for its use as a diagnostic agent for epileptic foci.
About Yokohama City University
Located in the international city of Yokohama, Yokohama City University has four campuses, five faculties, five graduate schools, two affiliated research centres, and two affiliated hospitals that serve as the bases for education, research, and medical care.
SOURCE Yokohama City University
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