The next steps toward this future are already underway. Pogue's team is looking to characterize how small of a region they can track the oxygenation from, and how fast they can take measurements. "Our goal is to produce oxygen images at video rate, with a spatial resolution that allows us to see radiobiologically relevant hypoxia nodules in the tumor of humans," explains Pogue.
Brian W. Pogue, PhD, is Co-Director of the Translational Engineering in Cancer Research Program at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center, MacLean Professor of Engineering at Dartmouth's Thayer School of Engineering, and Professor of Surgery at the Geisel School of Medicine at Dartmouth, and President and Co-Founder of DoseOptics, which develops camera systems and software for radiotherapy imaging of Cherenkov light for dosimetry. His research interests include optics in medicine, biomedical imaging to guide cancer therapy, molecular-guided surgery, dose imaging in radiation therapy, Cherenkov light imaging, image-guided spectroscopy of cancer, photodynamic therapy, and modeling of tumor pathophysiology and contrast.
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About Norris Cotton Cancer Center at Dartmouth-Hitchcock
Norris Cotton Cancer Center combines advanced cancer research at Dartmouth's Geisel School of Medicine with patient-centered cancer care provided at Dartmouth-Hitchcock Medical Center in Lebanon, NH, at Dartmouth-Hitchcock regional locations in Manchester, Nashua and Keene, NH, and St. Johnsbury, VT, and at partner hospitals throughout New Hampshire and Vermont. It is one of 51 centers nationwide to earn the National Cancer Institute's "Comprehensive Cancer Center" designation.
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