Professor Stavros Stivaros
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In a second group, 8 children presented with neurological problems but displayed none of the classic symptoms of Covid-19 such as difficulty breathing or loss of taste or smell. Sadly one of these children remains on inpatient on a ventilator also six months after presentation.
In a third group, 11 children developed a developed a delayed inflammatory response to Covid, known as multi-system inflammatory syndrome.
And in a final fourth group, 7 children had neurological symptoms and abnormal brain and spine imaging but could not be categorised into the other three groups.
Professor Stivaros added: “It’s important to stress that most children with Covid related neurological illness will get better, but nevertheless it can rarely occur in previously healthy children.
“A small number of these previously healthy children will die from either directly from Covid-19 or from of their increased sensitivity to other infections and some can get neurological complications from a delayed response to their Covid-19 infection.
“We also suspect that children who were neurologically impaired through COVID-19 earlier in the pandemic might not have been identified.
“That could be explained by an absence of available PCR testing or because the atypical or delayed symptoms shown by children were not immediately identified as being COVID-19 related.”
Of the 111 respondents to the American Society of Pediatric Neuroradiology international call for COVID-19 related cases, 80 cases were submitted for review with 42 either being excluded or being withdrawn leaving 38 children reported in the study.
And of the 38 children with neurological disease related to SARS-CoV-2 infection 13 came from France, 8 from the UK, 5 from the USA, 4 from Brazil, 4 from Argentina, 2 from India, 1 from Peru, and 1 from Saudi Arabia.
The paper ‘Neuroimaging manifestations in children with SARS-CoV-2 infection: a multinational, multicentre collaborative study’ is published in Lancet Child and Adolescent HealthBack to HCB News