The economic model was designed using a decision tree framework simulating costs and outcomes of continuous Nellcor™ pulse oximetry and Microstream™ capnography monitoring* versus intermittent pulse oximetry monitoring* for patients at high risk, high and intermediate risk, and any risk of respiratory depression based on their PRODIGY score(opens new window). Patients' PRODIGY score was derived from five independent patient characteristics — age, gender, sleep-disordered breathing, opioid naivety, and chronic heart failure. The model applied the results of the PRODIGY study to a hypothetical median-sized U.S. hospital with 2,447 patients receiving opioids on a medical surgical floor in a given year.

"Respiratory compromise is a common, costly, potentially deadly — and preventable — condition. RC is a leading cause of ICU admissions and is one of the key contributing factors for code blues,1,2" said Frank Chan, president of the Patient Monitoring business, which is part of the Medical Surgical Portfolio at Medtronic. "Medtronic has a deep-rooted history of discovering, developing, and commercializing transformative treatment options for patients globally. As RC continues to be studied, we are able to analyze these learnings and design innovative solutions to help physicians better care for their patients who may experience OIRD."


Additionally, the primary objective of the PRODIGY trial was to develop and validate a risk stratification tool to assist clinicians in the identification of high risk patients receiving opioids.3 The PRODIGY risk stratification tool may support the recent updates from The Joint Commission on monitoring of post-operative patients receiving opioids with the requirement of putting in place a mechanism to identify high risk patients.4

For additional information about the PRODIGY clinical trial, please visit: medtronic.com/prodigy(opens new window).


About Respiratory Compromise
Respiratory compromise is a potentially life-threatening, progressive condition negatively impacting a person's ability to breathe adequately to maintain oxygenation and carbon dioxide removal. Patients with respiratory depression may experience shallow, slow, or no breathing after opioid administration which undetected can lead to cardiopulmonary arrest and death.5 This condition is rapidly becoming the third-most costly hospital inpatient expense in the U.S., and dramatically increases the likelihood of adverse patient outcomes and cost of patient care.6 Not only is respiratory compromise common and dangerous, it has been very difficult to predict.7,8,9

Patient Monitors Homepage