“NorthStar continues to make tremendous progress in our mission to provide patients global access to our game-changing radiopharmaceuticals,” said Stephen Merrick, President and Chief Executive Officer of NorthStar Medical Radioisotopes. “We are well on our way to having dual production and processing pathways for Mo-99 that give additional domestic production capacity and security of supply to better meet customer demand. Our two facility expansion projects in Beloit, Wis. are moving to the final phase of activities required for FDA and WI-DHS approval and will augment current Mo-99 production and processing in Columbia, Mo. The Isotope Processing facility in Beloit will enable us to more than double our current Mo-99 processing capabilities. The new Mo-99 Accelerator Production facility will add significant Mo-99 capacity and enable flexible scheduling, including Sunday production, which is highly desirable for our radiopharmacy customers. Testing of the Accelerator Production and Isotope Processing equipment is underway, with commercial production expected at the start of 2023, pending appropriate licensure and FDA approval.

“Importantly, NorthStar is rapidly expanding its leadership position in the emerging area of therapeutic radioisotopes, which are used in targeted radiopharmaceutical therapy to treat cancer, respiratory and other diseases. NorthStar is defining the supply chain for scalable, reliable therapeutic radioisotope production. By applying our proven Mo-99 production development expertise and environmentally sound electron accelerator technology, we are well-positioned to be the first commercial-scale producer of actinium-225 (Ac-225) and copper-67 (Cu-67). NorthStar is further investing in the future with our groundbreaking on a first-of-its-kind Therapeutic Radioisotope Production facility, exclusively dedicated to commercial-scale production of our no-carrier added (n.c.a.) Ac-225. In addition, we have expanded our pipeline with the recent addition of iodine-123 capsules to our future product offering, pending appropriate licensure and FDA approval, the development of our fibrin-specific diagnostic imaging candidate remains on track and we are evaluating additional potential opportunities with specialized SPECT radiopharmaceuticals and therapeutic radioisotopes to address unmet healthcare needs.”


Mr. Merrick continued, “We are extremely grateful to all of our partners and stakeholders in supporting our progress: the U.S. Department of Energy’s National Nuclear Security Administration and National Laboratories, the U.S. Food and Drug Administration, the Wisconsin Department of Health Services, our private commercial investors, NorthStar’s dedicated employees, our supply chain partners, and our customers. In particular, we would like to recognize the support that our partners at the University of Missouri Research Reactor (MURR®), with whom we jointly produce Mo-99 in Columbia, Missouri, continue to provide to NorthStar. IBA (Ion Beam Applications S.A., EURONEXT), a leading global supplier of accelerators that is focused on bringing integrated and innovative solutions for the diagnosis and treatment of cancer, continues to be a tremendous collaborator in our efforts. We are also proud to help showcase both the City of Beloit and Wisconsin as pioneers and leaders in technology innovation and sustainable radioisotope production. Our expansion activities are supported by Corporate Contractors Incorporated (CCI), the lead contractor, Springs ATG (Advanced Technology Group) and Von Gahlen, a leading global supplier of state-of-the-art shielding solutions for nuclear medicine and radiopharmacy.”

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