Reduced risk of future blockages. OCT guidance was associated with a 64% reduction in ST rates, resulting in a statistically significant difference compared to angiographic guidance.
Additional safety benefits. OCT guided PCIs vs. angiography was associated with a 39% reduction in cardiac death and 24% reduction in target vessel myocardial infarction, respectively.

While the study met its primary imaging endpoint of improving MSA, it did not achieve superiority in reducing the primary clinical endpoint, target vessel failure (TVF), a composite of cardiac death, myocardial infarction (MI) and target vessel revascularization (TVR) at two years. Despite the numeric reductions in both cardiac death and target vessel MI when OCT was used, the lack of differentiation in TVR may have been impacted by the COVID-19 pandemic, regional variations in routine practice, and access to healthcare.


"The ILUMIEN IV data demonstrate the impact that OCT guidance can have when treating patients with complex coronary disease," said Nick West M.D., chief medical officer and divisional vice president of global medical affairs at Abbott’s vascular business. "In these cases, angiography alone simply cannot match the precision afforded by OCT to determine a treatment plan."

Ultreon™ Software, the latest OCT offering from Abbott, is the only intracoronary imaging solution on the market powered by artificial intelligence, guiding stents to be placed with precision. This leading technology provides enhanced views of coronary anatomy and blockages to help support physicians’ decision-making in real time.

About Abbott:
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 115,000 colleagues serve people in more than 160 countries.

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