Preliminary results of a multi-center study using shear wave elastography technology
Phase one of the study conducted across 17 centers in the United States and Europe, endeavored to define a scientific model of 1,000 patients to determine if shear wave elastography improves diagnosis, when added to ultrasound, by providing complementary ultrasound information. This required identifying the criteria of an elastography image that would increase sensitivity and specificity when added to ultrasound criteria to improve lesion characterization and eventually improve a BI-RADS score.
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The shear wave elastography criteria or features studied for each lesion were: size, shape, average value of elasticity, homogeneity, orientation and contrast of elasticity between lesion and fatty tissue. Key findings found that shear wave elastography provides both qualitative and quantitative reproducibility.* Another major outcome of the study showed that when shear wave elastography features are added to ultrasound features, there is a significant increase in correct classification of lesions (from 73.1% Ultrasound BI-RADS alone to 87% BI-RADS plus 2 shear wave elastography features).
Shear wave elastography holds great hope for improving lesion classification and increasing diagnostic accuracy.
*Quantification Tool Exist Outside the USA
Dr. Cosgrove is emeritus professor of clinical ultrasound at the Imperial College School of Medicine. He is also a consultant in radiology for the Hammersmith Hospital in London and the lead investigator in the Assessment of the Clinical Value of SuperSonic Shearwave Elastography Study.
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