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Australia's Prince of Wales Hospital Launches New Era of Targeted Lung Cancer Treatments with Elekta's Advanced 4D Motion Manage

Press releases may be edited for formatting or style | October 31, 2011
SYDNEY /PRNewswire/ -- To successfully irradiate a moving lung tumor requires doctors to find a way either to stop the tumor from moving or a means to compensate for its motion. On September 8, clinicians at Prince of Wales Hospital Cancer Centre (Randwick, New South Wales) chose the second option, using Elekta's Symmetryâ„¢ respiratory motion management software for the first time to treat a 75-year-old male patient with a tumor that moved back and forth with his breathing. Symmetry enables physicians to visualize the tumor's complete range of motion and then ensures that the tumor is always positioned in the treatment beam regardless of its movement.

Accurate treatment of this patient's tumor, a primary, malignant non-small cell cancer (NSCLC) in the upper lobe of the left lung, was critical due to the therapy approach used. Prince of Wales Hospital clinicians used hypofractionated Stereotactic Body Radiation Therapy (SBRT), which called for precise immobilization of the patient's body to enable just three treatment sessions (i.e., fractions), each using a highly potent radiation dose.

"The whole concept of hypofractionated stereotactic treatment relies on accurate and precise planning datasets and treatment verification systems," says Wenchang Wong, M.D., radiation oncologist at Prince of Wales Hospital. "Symmetry afforded us clear visualization of the tumor at the treatment couch and gave me confidence that treatment delivery would be safe and reproducible for this patient."
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Symmetry, a feature set of Elekta's X-ray Volume Imaging (XVI) software package, enables clear visualization of moving lung tumors by providing a dynamic fourth dimension (4D) of motion to enhance image guidance with the patient in the treatment position.

"Conventional cone beam CT provides only a static, blurred image of a moving lung tumor that cannot tell us in which part of the respiratory cycle it was captured," Dr. Wong explains. "Conversely, Symmetry provides a dynamic 4D cine/picture of the movement of the tumor mass throughout the entire respiratory cycle. This is especially important in lung cancer treatment given the natural excursion of the tumor with the breathing cycle. Symmetry enables us to see the tumor's movement in real time."

Symmetry: From planning to treatment

Hypofractionated SBRT of lung tumors at Prince of Wales involves several Elekta solutions, encompassing planning through to treatment.

To ensure a consistent patient breathing pattern during treatment, planning CT scans are performed with Active Breathing Coordinatorâ„¢. This Elekta technology enables acquisition of a breathing trace that shows peak inhalation and exhalation points during normal breathing.

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