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High radiotherapy dose boosts prospects for children with brain cancer

by Thomas Dworetzky, Contributing Reporter | April 28, 2015
European News Rad Oncology

"Our work, which involved a large number of children with ependymoma, has confirmed that the treatment we carry out today is better than it was a few years ago, but there is still much work to be done. For example, we found that children younger than three, and those with more aggressive disease had a poorer outcome, and we need to look further at how we can improve their treatment, as well as identifying other children at high risk of relapse," Dr. Ducassou reported in a statement.

Professor Philip Poortmans, president of ESTRO, reflected in a statement on the pair of studies. He noted that they “demonstrate that a clear dose-effect relationship exists for tumor control and survival. While the increase from 54 to 59.4 Gy that was adopted first improves disease control and survival in a population-based study, a new study is planned to confirm the results of increasing the dose by a further 8 Gy, delivered with highly directed radiation therapy techniques that give a very localized dose to the target volume, with a low dose to the surrounding normal tissues."

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