VIENNA--(BUSINESS WIRE)--Baxter International Inc. (NYSE:BAX), a leading provider of dialysis therapies, previewed THERANOVA, a new class of dialysers1,2 with the potential to significantly advance renal care, at the 53rd Congress of the European Renal Association and European Dialysis and Transplant Association (ERA-EDTA).
THERANOVA is an innovative dialyser, designed to extend the range of toxins that can be filtered from the blood during haemodialysis. THERANOVA dialysers are indicated for treatment of chronic and acute renal failure by haemodialysis.
People with end-stage kidney disease retain toxins, including mid-sized and large solutes that may affect a range of biological functions and contribute to elevated cardiovascular risk.3 Standard haemodialysis is effective at removing small solutes, such as urea, but is ineffective in removing larger toxins.4
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In data being presented at the Congress, the permeability and selectivity properties of the THERANOVA membrane demonstrated significantly higher mean overall toxin clearance compared to the currently marketed high-flux dialysers (Abstract #SP416).
In vitro studies show that the THERANOVA dialyser delivers clearances of large uremic toxins (such as β-2 microglobulin) that are equivalent to and may exceed those of a hemodiafilter used in high-volume hemodiafiltration (HDF) mode.5,6 HDF is a dialysis therapy that also targets larger molecules.
''Our ultimate goal is to introduce innovations that will enable haemodialysis to more closely mimic the function of the natural kidney,'' said Marcus Schabacker, corporate vice president and chief scientific officer, Baxter. ''With THERANOVA, we are introducing an innovative dialyser that has the potential to improve care for the more than two million people globally who rely on haemodialysis. THERANOVA offers clinicians a more efficient way to deliver haemodialysis without sacrificing performance.''
In addition to its unique filtration profile, THERANOVA was designed to work with most standard haemodialysis machines. This eliminates the need for special equipment and ultrapure fluids, which is required for HDF. By providing HDF performance from a standard haemodialysis treatment, while avoiding the costs and complexity associated with high-volume HDF, THERANOVA has the potential to raise the standard of care for haemodialysis patients.
Building on 60 years of scientific expertise in haemodialysis and advanced membrane technology, Baxter researchers developed THERANOVA at its R&D facility in Hechingen, Germany.
