The panel also considered the appropriateness of using intensity-modulated radiation therapy (IMRT) in place of three-dimensional conformal radiation therapy (3-D CRT) in neoadjuvant and adjuvant settings. IMRT is an advanced RT technique that delivers more focal radiation doses and spares more radiosensitive healthy tissue than with 3-D CRT. For each of the three treatment scenarios (neoadjuvant RT alone, neoadjuvant chemoradiation, adjuvant chemoradiation), panelists rated IMRT as May Be Appropriate, noting both upsides, such as reduced toxicity, as well as downsides, such as the higher financial costs, of using the technique.
The clinical practice statement was approved by ASTRO's Board of Directors following a four-week period of public comment. The ten-member expert panel included radiation oncologists, medical oncologists, colorectal surgeons, a gastroenterologists and a general internal medicine doctor: Patrick Francke, MD, Salma Jabbour, MD, Harvey Mamon, MD, PhD, Richard Goldberg, MD, Bruce Lin, MD, George Chang, MD, Julio Garcia-Aguilar, MD, PhD, David Dietz, MD, Jeffrey Tokar, MD, and Marilyn Schapira, MD, PhD.
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For a copy of the complete guideline, contact ASTRO's media relations team at press@astro.org or 703-286-1600. Learn more about PRO at www.practicalradonc.org.
ABOUT ASTRO
ASTRO is the premier radiation oncology society in the world, with more than 10,000 members who are physicians, nurses, biologist, physicists, radiation therapists, dosimetrists and other health care professionals that specialize in treating patients with radiation therapies. As the leading organization in radiation oncology, the Society is dedicated to improving patient care through professional education and training, support for clinical practice and health policy standards, advancement of science and research, and advocacy. ASTRO publishes three medical journals, International Journal of Radiation Oncology • Biology • Physics (www.redjournal.org), Practical Radiation Oncology (www.practicalradonc.org) and Advances in Radiation Oncology (www.advancesradonc.org); developed and maintains an extensive patient website, RT Answers (www.rtanswers.org); and created the Radiation Oncology Institute (www.roinstitute.org), a nonprofit foundation to support research and education efforts around the world that enhance and confirm the critical role of radiation therapy in improving cancer treatment. To learn more about ASTRO, visit www.astro.org.
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