John Floberg, MD, PhD, PGY-3 resident, Washington University/Barnes-Jewish Hospital, St. Louis. With his ASTRO seed grant, Floberg aims to develop a predictive biomarker for cervical cancer. He will investigate the use of functional imaging methods, including positron emission tomography (PET) and magnetic resonance imaging (MRI), to assess the state of cervical cancer cells and predict how tumors will respond to therapies designed to enhance radiation sensitivity.
Chirayu G. Patel, MD, MPH, radiation oncology resident, Vanderbilt University Medical Center, Nashville, Tennessee. Patel will use his seed funding to investigate altered tumor metabolism, particularly tumor reliance on the amino acid glutamine, as a mechanism of radioresistance in non-small cell lung cancer. He will explore if this altered metabolism occurs by increased scavenging of reactive oxygen species and will employ small molecule inhibitors to disrupt glutamine metabolism.
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Cheng-Chia "Fred" Wu, MD, PhD, radiation oncology resident, NewYork-Presbyterian/Columbia University Medical Center, New York. With his ASTRO grant, Wu will investigate if the integrity of the blood brain barrier limits communication between the central nervous system and the systemic immune systems, namely whether the disruption of the blood brain barrier with focused ultrasound can enhance the effects of checkpoint inhibitor-targeted therapy and the abscopal effect in the brain.
All awardees must submit a report to ASTRO at the midterm and the conclusion of their research, and they are strongly encouraged to submit their study as an abstract in a subsequent ASTRO Annual Meeting. The grant winners are selected by ASTRO's Research Grants Evaluation Committee within the Science Council and approved by the ASTRO Board of Directors.
For more information about ASTRO's grants and awards, visit https://www.astro.org/Funding-Opportunities.aspx.
ABOUT ASTRO
ASTRO is the premier radiation oncology society in the world, with more than 10,000 members who are physicians, nurses, biologist, physicists, radiation therapists, dosimetrists and other health care professionals that specialize in treating patients with radiation therapies. As the leading organization in radiation oncology, the Society is dedicated to improving patient care through professional education and training, support for clinical practice and health policy standards, advancement of science and research, and advocacy. ASTRO publishes three medical journals, International Journal of Radiation Oncology • Biology • Physics (www.redjournal.org), Practical Radiation Oncology (www.practicalradonc.org) and Advances in Radiation Oncology (www.advancesradonc.org); developed and maintains an extensive patient website, RT Answers (www.rtanswers.org); and created the Radiation Oncology Institute (www.roinstitute.org), a non profit foundation to support research and education efforts around the world that enhance and confirm the critical role of radiation therapy in improving cancer treatment. To learn more about ASTRO, visit www.astro.org.
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