English
Chinese (Simplified)
French
Portuguese
Spanish
German
Clean Sweep Live Auction on Wed. May 1st. Click to view the full inventory
| DOTmed Home | MRI | Oncology | Ultrasound | Molecular Imaging | X-Ray | Cardiology | Health IT | Business Affairs |
| News Home | Parts & Service | Operating Room | CT | Women's Health | Proton Therapy | Endoscopy | HTMs | Pediatrics |
Forward
Print
Comment
Molecular Imaging Homepage
Louisiana getting $14 million Center for Molecular Imaging and Therapy Increasing research opportunities, collaboration and radiopharmaceuticals
PET uncovers abnormal tau deposits associated with CTE in live subjects May enable diagnosis of CTE in living people one day
DOE transfers land to Coquí Pharma for isotope production facility Will be used primarily to produce Mo-99
Amyloid PET scans help with Alzheimer's clinical management New insights from the 11,000 patient IDEAS study
United Imaging's total-body PET scanner shows promise in four new studies Faster scans, lower dose and 'a level of detail never seen in PET'
NorthStar buys IBA electron accelerators for Mo-99 production Will increase production capacity and efficiencies
RadioMedix and Vect-Horus to develop brain theranostic agent for brain cancer Provide diagnosis and treatment of Glioblastoma Multiforme (GBM)
NIH awards $1.8 million to Magnetic Insight for neurovascular MPI Detects magnetic nanoparticle tracers, enables deep-tissue imaging
DOE to cut Moly-99 deals with four US firms Could be as much as $15 million per company, with partners matching awarded amounts
Women's brains appear three years younger than men's at the same age: PET study A machine-learning algorithm assisted with the analysis
X-rays may no longer remain as only modality to image bones
The team accomplished this by attaching luminescent compounds to tiny gold structures that, in turn, cling to cracks or weaknesses in bone and provide visualization of the structure. Their work was published in the research journal Chem.
RaySafe helps you avoid unnecessary radiation
RaySafe solutions are designed to minimize the need for user interaction, bringing unprecedented simplicity & usability to the X-ray room. We're committed to establishing a radiation safety culture wherever technicians & medical staff encounter radiation.
"We were able to develop ways of not only visualizing the small micro-cracks in the bone, but also map the entire area in 3-D using the so called Z-stacking method and two-photon excitation," Thorfinnur Gunnlaugsson, Professor of Chemistry at Trinity College Dublin told HCB News.
He added that their research findings are the result of collaboration with Clive Lee, M.D., Ph.D. at the Department of Anatomy in the Royal College of Surgeons.
The technique could have major implications in the diagnoses of bone strength. It also could provide a detailed blueprint of the extent and precise positioning of any bone weakness or injury. This diagnostic knowledge could help prevent the need for bone implants and act as an early-warning system for people at a high risk of degenerative bone diseases, such as osteoporosis.
The science works by creating a carrier composed of biocompatible gold nano particles. According to Gunnlaugsson, a "bone crack targeting molecule" is functionalized by adding a molecule that binds to lanthanide ions and europium. This, in turn, creates a luminescent "assembly" which is applied to the bone and brought to life with a florescence microscope.
"As the lanthanide ion can be changed out for a gadolinium we should, in theory, be able to convert these luminescent imaging agents into magnetic resonance imaging agents," explained Gunnlaugsson. "That is something we are also working on at present. However, the sensitivity of that imaging platform is not as sensitive as the one developed here."
Gunnlaugsson acknowledged their 3-D bone scanning protocol has a way to go before it is applied for human diagnostics, adding that progress will depend on interdisciplinary research and funding.
"We are some distance away ... But the future is very bright for this technique and it will, hopefully, be a method that can complement the use of X-rays," he said.
Gunnlaugsson added that the two-photon excitation used in the procedure is a "real future application". It allows for deeper penetration of light that is much less harmful to patients than high energy light.
The work was funded by Science Foundation Ireland and by the Irish Research Council.
Molecular Imaging Homepage
- Louisiana getting $14 million Center for Molecular Imaging and Therapy
- PET uncovers abnormal tau deposits associated with CTE in live subjects
- DOE transfers land to Coquí Pharma for isotope production facility
- Amyloid PET scans help with Alzheimer's clinical management
- United Imaging's total-body PET scanner shows promise in four new studies
You Must Be Logged In To Post A CommentRegisterRegistration is Free and Easy. Enjoy the benefits of The World's Leading New & Used Medical Equipment Marketplace. Register Now! |
|
