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MRI Homepage

Researchers developing miniaturized device to capture brain waves during MR Aiming for a better way to read brain waves

FDA gives approval to neonatal brain MR scanner Features a temperature-controlled incubator that goes directly into the system

Henry Ford Cancer Institute treats first patient with ViewRay's MRIdian Linac 'Takes off the blindfold' for radiation oncologists

fMR imaging reveals how well PTSD patients will respond to therapy Paving the way to more personalized treatment

Stanford Medicine's new virtual reality system assists surgeons and calms patients An immersive trip inside the brain

Researchers develop metal-free MR contrast agent for high-risk patients Will gadolinium become a thing of the past?

Researchers create tumor-targeting MR contrast agent using human proteins May be a viable alternative to gadolinium

Gadolinium retention may be more widespread than previously thought Why that is, remains to be understood

Supplemental breast MR superior to ultrasound for screening breast cancer survivors But what about cost-effectiveness?

German researchers find sweet alternative to conventional MR contrast agents Imaging with glucose using 7T MR scanner

Breast MR image shows a suspicious
enhancing mass in the left breast

MR breast screening benefits women at average risk

by Lauren Dubinsky , Senior Reporter
Breast MR is recommended for women with a high risk of developing breast cancer, but a new German study found that those at average risk can also greatly benefit from the exam. The results were published online in the journal Radiology.

A team led by Dr. Christiane Kuhl of RWTH Aachen University investigated the impact of breast MR on 2,120 women between the ages of 40 and 70 who had less than a 15 percent lifetime risk of breast cancer. From 2005 to 2013, the women with dense breasts had normal screening mammography and ultrasound and the rest had normal screening mammograms.

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They found that breast MR detected 60 additional breast cancers, including 40 invasive cancers. The overall supplemental cancer detection rate was 15.5 percent per 1,000 women.

Out of the 60 cancers detected, 59 were found only with MR, one was found also by mammography and none by mammography or ultrasound alone.

The researchers concluded that MR is a useful supplemental screening tool for women at average risk, especially those with dense breasts, and that it's superior to ultrasound for this indication.

This study, as well as previous research, confirms that MR is also able to detect more aggressive types of cancers called interval cancers. These cancers "exhibit an adverse biologic profile and are the main driver of breast cancer mortality," according to Kuhl.

“The interval cancer rate in our study was zero percent. Not a single cancer was undetected that became palpable,” she added. “This suggests that MRI finds breast cancers that mammography would also find, but MR detects them earlier, and it finds the cancers which, if MR had not been done, would have progressed to interval cancers.”

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