About Brainlab
Brainlab develops, manufactures and markets software-driven medical technology, enabling access to advanced, less invasive patient treatments.
Brainlab technology powers treatments in radiosurgery as well as numerous surgical fields including neurosurgery, orthopedic, ENT, CMF, spine and trauma. Founded in Munich in 1989, Brainlab has over 11,700 systems installed in over 100 countries.
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About MDNA55
MDNA55 is a targeted dual-action immunotherapeutic agent designed to purge tumor cells and adjacent immunosuppressive cells in the tumor microenvironment that over-express the interleukin-4 receptor (IL4R), which is frequently expressed in a majority of patients with glioblastoma and common in other aggressive forms of cancer. By directly eliminating tumor cells and boosting a therapeutic immune response, MDNA55 provides a two-pronged approach to treat cancer. MDNA55 has received Fast Track Designation from the FDA and Orphan Drug Status from both the FDA and EMA. Earlier results from three Phase 1 and 2a clinical trials in 66 patients with recurrent glioblastoma showed potent anti-tumor effects without drug-related systemic toxicity in the majority of patients.
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