“It is a trial that will enable us to gain knowledge about how to move beyond our current ‘one size fits all’ approach, where we screen women the same way, based on age-specific guidelines, to more personalized strategies that tailor screening to each woman’s own genetics and individual breast cancer risk factors,” Dr. Etta D. Pisano, the study chair and a professor in residence of radiology at Beth Israel Deaconess Medical Center and Harvard Medical School told HCB News. “In addition to finding out what technology works best, TMIST is about learning how to help individual women get what they need to avoid death from breast cancer.”

The study is now open for enrollment at several mammography clinics in the U.S., with more planning to begin enrollment over the next several months. About 100 U.S. clinics in total plan to participate in the trial, along with a few locations in Canada where the findings from a smaller lead-in study of 3,000 women are being used to inform TMIST.


Women will be informed about enrolling in the trial when it is time to schedule their next routine mammogram.

Back to HCB News

Women's Health Homepage