May 02, 2018 -- OXFORD, England & BURLINGTON, Mass.--(BUSINESS WIRE)--Blue Earth Diagnostics, a leading molecular imaging diagnostics company, today announced that it has signed an exclusive, worldwide agreement with Scintomics GmbH, Germany, a specialist in radiopharmaceuticals and radiopharmaceutical technologies. Under the terms of the agreement, Blue Earth Diagnostics has acquired the exclusive worldwide rights to a broad family of Prostate Specific Membrane Antigen (PSMA)-targeted radiohybrid ("rh") agents for cancer imaging, together with an exclusive option to explore therapeutic applications.

"This agreement supports our strategic focus and is the next step in advancing our mission to develop and deliver products that address unmet medical needs in prostate cancer," said Jonathan Allis, D. Phil., CEO of Blue Earth Diagnostics. "Blue Earth Diagnostics is working to assemble a world-leading prostate cancer imaging portfolio. To that end, 18F rhPSMA and Axumin® have unique mechanisms of action which we believe may ultimately allow physicians and their patients to select the diagnostic agent most appropriate to each specific clinical situation. 18F rhPSMA is an ideal strategic expansion of our imaging portfolio that also enables us to broaden into therapeutic applications of this technology."

The agreement expands Blue Earth Diagnostics' oncology portfolio and builds on the company's proven track record and depth of expertise in the rapid development and global commercialization of radiopharmaceuticals for cancer. Blue Earth Diagnostics will drive development of a lead 18F rhPSMA imaging compound and collaborate with Scintomics to identify optimized therapeutic candidates for future development. Acquisition of the rights to this advanced technology provides strong synergies with Axumin® (fluciclovine F 18), Blue Earth Diagnostics' approved and commercially available PET/CT imaging agent for use in patients with a rising PSA after prior prostate cancer treatment.
Scintomics' theranostic "radiohybrid" technology allows for the efficient labelling of PSMA-targeted agents with imaging radioisotopes, such as 18F, or therapeutic radioisotopes such as 177Lu, providing the ability to potentially be used either as a prostate cancer imaging agent or as a therapeutic agent. If approved, these innovative compounds offer the possibility of "precision medicine" for men with prostate cancer.

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