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Molecular Imaging Homepage
RadioMedix and Vect-Horus to develop brain theranostic agent for brain cancer Provide diagnosis and treatment of Glioblastoma Multiforme (GBM)
NIH awards $1.8 million to Magnetic Insight for neurovascular MPI Detects magnetic nanoparticle tracers, enables deep-tissue imaging
DOE to cut Moly-99 deals with four US firms Could be as much as $15 million per company, with partners matching awarded amounts
Women's brains appear three years younger than men's at the same age: PET study A machine-learning algorithm assisted with the analysis
Dennis Durmis MITA names chair of board of directors
Researchers find new PET tracer that better detects melanoma than 18F-FDG 18F-P3BZA could become the new gold standard
RadioMedix scores $2 million contract for Targeted Alpha-emitter therapy Treatment for neuroendocrine tumors
FDA clears United Imaging's total-body PET scanner Creating 3D images of entire human body in 15-30 seconds
FDA clears MIM SurePlan molecular radiotherapy software Can measure the absorbed dose from MRT for individual patients
Rob Beanlands ASNC names president for 2019
BWXT developed a new medical isotope technology to produce Mo-99
“While neutron capture was the original method for producing Mo-99, Tc-99m generators using neutron capture Mo-99 historically produced a far less concentrated elution of Tc-99m,” Dr. Jonathan Cirtain, VP of advanced technologies at BWXT, told HCB News. “Therefore, [it] limited the types of kits and doses of imaging agent that could be effectively compounded, administered and imaged.”
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However, the new technology produces a proprietary Mo-99 product that when eluted, produces an eluent of similar specific activity to fission-based Tc-99m generators that are available today. That means radiopharmacies can use BWXT Tc-99m generators in the same way they use current fission-based Tc-99m generators.
But Cirtain noted that unlike the traditional process of producing Mo-99 and Tc-99m generators from a nuclear fission process, this process doesn’t use fission. As a result, it doesn’t produce uranium or other fission products as waste, which is costly and difficult to dispose of and can be a proliferation concern.
BWXT expects this new medical isotope technology to provide a reliable domestic supply of Mo-99 and Tc-99m for North America. But the company has competition from a handful of companies with the same goal.
“We are confident because we have experience in this area developed over decades of work, and we’ve had a highly successful development program, including supplemental assistance from outside expertise when needed,” said Cirtain.
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