dismiss

Clean Sweep Live Auction on Wed. February 27th. Click to view the full inventory

DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
SEARCH
Current Location:
>
> This Story


Log in or Register to rate this News Story
Forward Printable StoryPrint Comment
advertisement

 

advertisement

 

Molecular Imaging Homepage

Women's brains appear three years younger than men's at the same age: PET study A machine-learning algorithm assisted with the analysis

Dennis Durmis MITA names chair of board of directors

Researchers find new PET tracer that better detects melanoma than 18F-FDG 18F-P3BZA could become the new gold standard

RadioMedix scores $2 million contract for Targeted Alpha-emitter therapy Treatment for neuroendocrine tumors

FDA clears United Imaging's total-body PET scanner Creating 3D images of entire human body in 15-30 seconds

FDA clears MIM SurePlan molecular radiotherapy software Can measure the absorbed dose from MRT for individual patients

Rob Beanlands ASNC names president for 2019

Former South African nuclear executives to appeal suspensions in court Involves monthslong shutdown of NTP Radioisotopes medical isotope plant

FDA grants Fast Track designation to 64-Cu-Dotatate Used in PET diagnostic exams for suspected neuroendocrine tumors

Editorial takes aim at NRC efforts to lower the bar for nuclear medicine providers 'The NRC has abdicated its role as a protection agency for patients' say authors

Radiolabeled small molecules bind to
fibroblast activation proteins in
cancer-associated fibroblasts found
within the tumor stroma

New PET imaging method may yield benefits over FDG for detecting certain cancers

by Lauren Dubinsky , Senior Reporter
German researchers have developed a PET imaging method that may raise the bar on diagnosing certain cancers.

The method targets cancer-associated fibroblasts (CAFs), which have been linked to tumor growth and are present in over 90 percent of epithelial carcinomas such as pancreatic, colon and breast cancer. The team created a PET tracer based on a FAP-specific enzyme inhibitor (FAPI).

Story Continues Below Advertisement

Has exclusive distribution agreement with DDD to sell new Camera systems

UMRi provides the very best new & refurbished gamma cameras, quality parts &repair services. We also rebuild & replace camera detectors, move camera systems across town or across the country. Call us at 888-239-3510



For a study recently published in the Journal of Nuclear Medicine, they tested the gallium-68-labeled FAPI tracer and a 18F-FDG PET tracer in mouse models as well as a proof-of-concept PET/CT study that involved three patients.

“The competing tracer is FDG, which is hard to beat,” Dr. Uwe Haberkorn of the University Hospital of Heidelberg, told HCB News. “However, we think that due to the high contrast [of] FAPI, [it] may be superior in peritonitis carcinomatosa, liver tumors/metastases, brain metastases, carcinoma of unknown primary, staging of breast cancer and head and neck cancer.”

The study results demonstrated that gallium-68-labeled FAPI has high tumor uptake and clears from the body at a fast rate. That means it generates high-contrast images and has a low chance of binding to healthy tissue in both animals and patients.

According to Haberkorn, issues arise when using 18F-FDG PET to diagnose lung cancer because inflammatory lymph nodes result in false positives. He believes gallium-68-labeled FAPI could be used instead.

“Besides cancer, FAPI may also be used for benign diseases with remodelons such as fibroses, artherosclerosis, rheumatoid arthritis, sarcoidosis, etc.,” he added.

Molecular Imaging Homepage


You Must Be Logged In To Post A Comment

Advertise
Increase Your
Brand Awareness
Auctions + Private Sales
Get The
Best Price
Buy Equipment/Parts
Find The
Lowest Price
Daily News
Read The
Latest News
Directory
Browse All
DOTmed Users
Ethics on DOTmed
View Our
Ethics Program
Gold Parts Vendor Program
Receive PH
Requests
Gold Service Dealer Program
Receive RFP/PS
Requests
Healthcare Providers
See all
HCP Tools
Jobs/Training
Find/Fill
A Job
Parts Hunter +EasyPay
Get Parts
Quotes
Recently Certified
View Recently
Certified Users
Recently Rated
View Recently
Certified Users
Rental Central
Rent Equipment
For Less
Sell Equipment/Parts
Get The
Most Money
Service Technicians Forum
Find Help
And Advice
Simple RFP
Get Equipment
Quotes
Virtual Trade Show
Find Service
For Equipment
Access and use of this site is subject to the terms and conditions of our LEGAL NOTICE & PRIVACY NOTICE
Property of and Proprietary to DOTmed.com, Inc. Copyright ©2001-2019 DOTmed.com, Inc.
ALL RIGHTS RESERVED