Poster Presentations
Tuesday, Oct 23, 1:00PM-2:30PM, Innovation Hub, Exhibit Hall 3

Dosimetric Evaluation of Treatment Plans for a Biology-Guided Radiation Therapy System in Treatment of Nasopharyngeal Cancer (TU_13_3236)
A Dosimetric Study to Assess the Feasibility of Prototype Treatment Planning Software for a New Biology-guided Radiation Therapy System (TU_1_3120)

Evaluation of a Prototype Treatment Planning System (TPS) for Biology-Guided Radiation Therapy (BgRT) in the Context of Stereotactic Body Radiation Therapy (SBRT) for Oligo-Metastases (TU_10_3209)
“We are presenting our results surrounding treatment plans that demonstrates the RefleXion machine may improve radiotherapy delivery for current indications such as head-and-neck, prostate, and esophageal cancers using a conventional CT-guidance approach,” said Jeffrey Wong, M.D. chair and professor, Department of Radiation Oncology at the City of Hope. “When combined with this platform’s potential to expand and efficiently treat metastatic disease, we are even more encouraged with these early results.”

Additionally, RefleXion will host a series of Office Hours in its booth, #1971, in Exhibit Hall C to allow peer-to-peer conversations with industry-leading RefleXion BgRT consortium sites from around the United States. Space is limited, so pre-registration is recommended.


About RefleXion BgRT
RefleXion’s platform enables a leap forward in the ongoing goal of conventional radiotherapy to manage motion, reduce tumor margins and diminish radiation toxicity, making it feasible to treat multiple tumors in the same session. Current radiotherapy systems require a margin of healthy tissue around the tumor to account for positional uncertainties such as involuntary patient movements and breathing. In many cases, this extra margin results in a significant amount of additional radiation delivered to the patient’s healthy tissue. If too much healthy tissue receives radiation and the patient nears threshold toxicity levels, less therapeutic radiation is available to ensure efficacy of treatment or to treat additional tumors. By using the tumor’s own emissions to guide radiation delivery, treatment margins and the subsequent radiation dose to healthy tissue may be significantly reduced.

Traditionally PET is used to form a complete image that takes up to an hour, during which time the tumor can change location. However, as the FDG is consumed, the emissions it generates are instantly available and reveal the cancer’s location. The RefleXion platform senses these emissions and rapidly responds by sending a beamlet of radiation down the emissions’ pathways toward the originating tumor. By treating tumors that uptake the PET tracer, BgRT makes it feasible to track and treat multiple tumors throughout the body in the same session, a game-changing advance over existing platforms.

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