However, the scans can't give clinicians detailed insight into patients' likely overall outcomes or on the likely effect of a therapeutic intervention.
Researchers used a mathematical software tool called TEXLab to identify the aggressiveness of tumours in CT scans and tissue samples from 364 women with ovarian cancer between 2004 and 2015.

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The software examined four biological characteristics of the tumours which significantly influence overall survival - structure, shape, size and genetic makeup - to assess the patients' prognosis. The patients were then given a score known as Radiomic Prognostic Vector (RPV) which indicates how severe the disease is, ranging from mild to severe.
The researchers compared the results with blood tests and current prognostic scores used by doctors to estimate survival. They found that the software was up to four times more accurate for predicting deaths from ovarian cancer than standard methods.
The team also found that five per cent of patients with high RPV scores had a survival rate of less than two years. High RPV was also associated with chemotherapy resistance and poor surgical outcomes, suggesting that RPV can be used as a potential biomarker to predict how patients would respond to treatments.
Professor Aboagye suggests that this technology can be used to identify patients who are unlikely to respond to standard treatments and offer them alternative treatments.
The researchers will carry out a larger study to see how accurately the software can predict the outcomes of surgery and/or drug therapies for individual patients.
The study was funded by the NIHR Imperial Biomedical Research Centre, the Imperial College Experimental Cancer Medicine Centre and Imperial College London Tissue Bank.
This research is an example of the work carried out by Imperial College Academic Health Science Centre, a joint initiative between Imperial College London and three NHS hospital trusts. It aims to transform healthcare by turning scientific discoveries into medical advances to benefit local, national and global populations in as fast a timeframe as possible.
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