DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Pediatrics
SEARCH
Current Location:
>
>
> This Story

Forward Printable StoryPrint Comment
advertisement

 

advertisement

 

Rad Oncology Homepage

Xstrahl spotlights new RADiant treatment system at Texas Dermatology Society spring meeting

Proton Therapy Center in Prague becomes first Czech clinic to order RayStation

Apollo Proton Cancer Centre, Chennai performs India's first total marrow irradiation procedure

BC Cancer researchers demonstrate the promise of a novel radiation treatment for metastatic cancer patients

Cyclotron for Varian ProBeam Compact installed at new treatment center in Singapore

Integrated Oncology Network and Gamma West announce transaction

AngioDynamics announces first patient enrolled in NanoKnife DIRECT clinical study for stage III pancreatic cancer treatment

Papua New Guinea hospital selects Varian's Halcyon radiotherapy system

LAP positions itself as a QA provider in radiation therapy

Varian and Shandong Cancer Hospital form proton therapy clinical application and research partnership in China

New trial seeks to reverse effects of dead brain tissue caused by radiation

Press releases may be edited for formatting or style
LOUISVILLE, Ky., May 14, 2019 /PRNewswire/ -- A new procedure pioneered by Norton Healthcare physician-scientists directly targets brain tissue affected by radiation necrosis.

"I started losing my sight and then passed out," Alyssa Coffey recalled about experiencing her first seizure.

Story Continues Below Advertisement

RaySafe helps you avoid unnecessary radiation

RaySafe solutions are designed to minimize the need for user interaction, bringing unprecedented simplicity & usability to the X-ray room. We're committed to establishing a radiation safety culture wherever technicians & medical staff encounter radiation.



Coffey was in the midst of training for an upcoming bodybuilding competition. A scan revealed the then 23-year-old New Jersey resident had an arteriovenous malformation (AVM), a tangle of abnormal blood vessels connecting arteries and veins in the brain.

To treat the AVM, doctors in her home state used radiation therapy. The radiation therapy treated the AVM, but Coffey experienced the severe side effect of radiation necrosis.

Radiation therapy is an effective way to treat certain brain AVMs. In up to 5 percent of cases, however, it can cause damage to the surrounding brain. This can result in radiation necrosis, when the nearby brain tissue becomes injured and dies.

The condition can be disabling, causing severe headaches, nausea and vomiting, seizures, cognitive issues and even death.

Doctors use a variety of medications, such as steroids, to manage the symptoms. None of the medications works very well, and all have serious side effects. There is no approved cure.

"It was miserable," Coffey said. "The necrosis impacted my ability to work. Going to the gym was out of the question."

Doctors in New Jersey suggested exploratory brain surgery, but Coffey felt it was too risky.

A NEW TRIAL FOR RADIATION NECROSIS

Last year, while on an AVM support group website, Coffey learned about a study at Norton Neuroscience Institute in Louisville, Kentucky, and the University of Kentucky that sought to reverse radiation necrosis.

The trial, led by Shervin Dashti, M.D., Ph.D., endovascular neurosurgeon with Norton Neuroscience Institute, is the first in the world to deliver a single small dose of the cancer drug Avastin directly to the area of the brain affected by the necrosis. Tom Yao, M.D., endovascular neurosurgeon with Norton Neuroscience Institute, and Justin Fraser, M.D., neurosurgeon with UK HealthCare, also are treating patients in the study.

Avastin previously has been used effectively to treat radiation necrosis. The medication is given through an IV, meaning the drug has to circulate through the body before only a small percentage reaches the brain. When the drug does reach the brain, it has a hard time penetrating because of a natural defense mechanism called the blood-brain barrier. Making matters worse, exposing the body to Avastin can result in brain bleeds, clots and uncontrolled high blood pressure.
  Pages: 1 - 2 - 3 >>

Rad Oncology Homepage


You Must Be Logged In To Post A Comment

Advertise
Increase Your
Brand Awareness
Auctions + Private Sales
Get The
Best Price
Buy Equipment/Parts
Find The
Lowest Price
Daily News
Read The
Latest News
Directory
Browse All
DOTmed Users
Ethics on DOTmed
View Our
Ethics Program
Gold Parts Vendor Program
Receive PH
Requests
Gold Service Dealer Program
Receive RFP/PS
Requests
Healthcare Providers
See all
HCP Tools
Jobs/Training
Find/Fill
A Job
Parts Hunter +EasyPay
Get Parts
Quotes
Recently Certified
View Recently
Certified Users
Recently Rated
View Recently
Certified Users
Rental Central
Rent Equipment
For Less
Sell Equipment/Parts
Get The
Most Money
Service Technicians Forum
Find Help
And Advice
Simple RFP
Get Equipment
Quotes
Virtual Trade Show
Find Service
For Equipment
Access and use of this site is subject to the terms and conditions of our LEGAL NOTICE & PRIVACY NOTICE
Property of and Proprietary to DOTmed.com, Inc. Copyright ©2001-2019 DOTmed.com, Inc.
ALL RIGHTS RESERVED