As a group, COVID-19 patients with hematologic (blood) cancers, such as leukemia and lymphoma, had the highest mortality rate: 37% (20 of 54 patients). For patients with solid malignancies, the mortality rate was 25% (41 of 164). Striking differences were observed among specific solid cancers: the mortality rate for patients with lung cancer was 55% and colorectal cancer was 38%, compared with mortality rates of 14% for breast cancer and 20% for prostate cancer.

Certain underlying conditions—older age, hypertension, heart disease, and chronic lung disease—were significantly associated with increased mortality among cancer patients with COVID-19.


A detailed analysis of patients with cancer who died from COVID-19 shows that more than half of these individuals—37 of 61—had been in places with a higher risk of exposure to COVID-19, such as nursing homes, hospitals or emergency departments within the 30 days before being diagnosed with COVID-19. This was before widespread social distancing had been implemented.

Montefiore has already changed clinical practice as a result of the study's findings, by using telemedicine and early and aggressive social distancing for cancer patients, and by opening a dedicated cancer outpatient and inpatient clinical service. It has also instituted bilingual peer counseling and deployed social workers and food deliveries to its at-risk population.

Montefiore is able to quickly identify patients with a known history of cancer who test positive for COVID-19 based on a daily collection and collation of data across the health system. This allows the care team to act immediately to ensure appropriate care for these individuals and track outcomes.

The study's other co-lead authors are Sanjay Goel, M.B.B.S., and Rafi Kabarriti, M.D. The paper is titled "Case Fatality Rate of Cancer Patients with COVID-19 in a New York Hospital System."

Additional Montefiore-Einstein authors are: Daniel Cole, M.D., Mendel Goldfinger, M.D., Ana Acuna-Villaorduna, M.D., Kith Pradhan, Ph.D., Raja Thota. M.S., Stan Reissman, M.S.W., Joseph A Sparano, M.D., Benjamin A. Gartrell, M.D., Richard V. Smith, M.D., Nitin Ohri, M.D., Madhur Garg, M.D., Andrew D. Racine, M.D., Ph.D., Shalom Kalnicki, M.D. and Roman Perez-Soler, M.D.

This study was supported in part by the Albert Einstein Cancer Center (P30CA013330).


About Montefiore Health System
Montefiore Health System is one of New York's premier academic health systems and is a recognized leader in providing exceptional quality and personalized, accountable care to approximately three million people in communities across the Bronx, Westchester and the Hudson Valley. It is comprised of 11 hospitals, including the Children's Hospital at Montefiore, Burke Rehabilitation Hospital and more than 200 outpatient ambulatory care sites. The advanced clinical and translational research at its medical school, Albert Einstein College of Medicine, directly informs patient care and improves outcomes. From the Montefiore-Einstein Centers of Excellence in cancer, cardiology and vascular care, pediatrics, and transplantation, to its preeminent school-based health program, Montefiore is a fully integrated healthcare delivery system providing coordinated, comprehensive care to patients and their families.

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