During his career at USC, Jackiewicz led Keck Medicine’s transformation into an academic health system in the highly competitive Southern California market. He is responsible for oversight of USC’s clinical activities, including the USC Norris Comprehensive Cancer Center, one of the first comprehensive cancer centers established in the United States; USC Care Medical Group, the medical faculty practice; Keck Medical Center of USC, which includes two acute care hospitals: 401-bed Keck Hospital of USC and 60-bed USC Norris Cancer Hospital; USC Verdugo Hills Hospital, a 158-bed community hospital; and more than 67 outpatient clinics throughout Southern California.

Prior to joining USC in 2012, Jackiewicz served as chief executive officer of UC San Diego Health and associate vice chancellor and chief financial officer of UC San Diego Health Sciences. As CEO, he helped lead the San Diego health system during one of its most expansive periods of growth as it moved into the top 10 nationally for grant funding from the National Institutes of Health, opened the Sulpizio Cardiovascular Center and renovated UC San Diego Medical Center. In his earlier role as associate vice chancellor and CFO for health sciences, he was responsible for administrative and business oversight of a clinical enterprise with more than 900 faculty, the School of Medicine and the Skaggs School of Pharmacy and Pharmaceutical Sciences.


Earlier in his career, Jackiewicz served as director of fiscal operations for the clinical practices of the University of Pennsylvania and director of business and financial operations in Penn’s Department of Medicine, senior associate chair for finance and administration in the Department of Medicine at Stanford University School of Medicine, and chief operating officer at Columbia University Medical Center.

He earned his master’s degree in public health, health policy and management from Columbia University and his bachelor’s degree in business administration from the University of Georgia. He is married to Carol Peden, MD, who serves as professor of anesthesiology and director for health system innovation at the Gehr Family Center for Health Sciences and Innovation at Keck Medicine of USC. Peden is also a senior associate tutor at the University of Oxford and an adjunct professor at the University of Pennsylvania.

O’Keefe will retire on July 24 after a distinguished career of more than 40 years in leadership roles in some of the nation’s top academic medical centers. She helped lead the University of Chicago Medical Center’s transformation into the UChicago Medicine health system.

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