"Our long-term goal is to transform the clinical management of patients with brain cancer by providing molecular signatures of the disease using noninvasive FUS-LBx," Chen said. "Research with the new funding has the potential to radically advance the diagnosis and monitoring of brain cancer patients without surgery."
This project has been a team effort among multiple departments within Washington University in St. Louis. Chen has been collaborating with Eric Leuthardt, MD, chief, Division of Neurotechnology, professor of neurological surgery, of neuroscience in the School of Medicine and of biomedical engineering and mechanical engineering & materials science in the McKelvey School of Engineering; Gavin Dunn, MD, PhD, associate professor of neurological surgery, of neurology and of pathology and immunology at the School of Medicine; Allegra Petti, assistant professor in the Department of Medicine, Division of Oncology; Aadel Chaudhuri, MD, PhD, assistant professor of radiation oncology in the School of Medicine; H. Michael Gach, associate professor of radiation oncology; Michael Talcott, DVM, director of veterinary surgical services in the Division of Comparative Medicine; and Xiaowei Wang at the University of Illinois Chicago on this project.
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The McKelvey School of Engineering at Washington University in St. Louis promotes independent inquiry and education with an emphasis on scientific excellence, innovation and collaboration without boundaries. McKelvey Engineering has top-ranked research and graduate programs across departments, particularly in biomedical engineering, environmental engineering and computing, and has one of the most selective undergraduate programs in the country. With 140 full-time faculty, 1,387 undergraduate students, 1,448 graduate students and 21,000 living alumni, we are working to solve some of society’s greatest challenges; to prepare students to become leaders and innovate throughout their careers; and to be a catalyst of economic development for the St. Louis region and beyond.
This work was supported by the National Institutes of Health (R01EB027223 and R01MH116981) and was partially supported by the NIH/National Center for Advancing Translational Sciences (UL1TR002345) and OVCR Seed Grant, Washington University in Saint Louis.
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