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Artificial intelligence models to analyze cancer images can take shortcuts that introduce bias for minority patients

Press releases may be edited for formatting or style | July 23, 2021 Artificial Intelligence

“The promise of artificial intelligence is the ability to bring accurate and rapid precision health to more people,” Pearson said. “In order to meet the needs of the disenfranchised members of our society, however, we have to be able to develop algorithms which are competent and make relevant predictions for everyone.”

The study, “The Impact of Site-Specific Digital Histology Signatures on Deep Learning Model Accuracy and Bias,” was supported by the National Institutes of Health, the National Cancer Institute, the Adenoid Cystic Carcinoma Research Foundation, the Cancer Research Foundation, and the American Cancer Society. Additional authors include Frederick M. Howard, James Dolezal, Sara Kochanny, Jefree Schulte, Heather Chen, Dezheng Huo, Rita Nanda, Olufunmilayo I. Olopade, Nicole Cipriani, and Robert L. Grossman from the University of Chicago; Lara Heij from University Hospital RWTH Aachen, Germany; and Jakob N. Kather from University Hospital RWTH Aachen, Germany, University of Leeds, United Kingdom, and University Hospital Heidelberg, Germany.

About the University of Chicago Medicine & Biological Sciences
The University of Chicago Medicine, with a history dating back to 1927, is one of the nation’s leading academic health systems. It unites the missions of the University of Chicago Medical Center, Pritzker School of Medicine and the Biological Sciences Division. Twelve Nobel Prize winners in physiology or medicine have been affiliated with the University of Chicago Medicine. Its main Hyde Park campus is home to the Center for Care and Discovery, Bernard Mitchell Hospital, Comer Children’s Hospital and the Duchossois Center for Advanced Medicine. It also has ambulatory facilities in Orland Park, South Loop and River East as well as affiliations and partnerships that create a regional network of care. UChicago Medicine offers a full range of specialty-care services for adults and children through more than 40 institutes and centers including an NCI-designated Comprehensive Cancer Center. Together with Harvey-based Ingalls Memorial, UChicago Medicine has 1,296 licensed beds, nearly 1,300 attending physicians, over 2,800 nurses and about 970 residents and fellows.

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