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Prothena to use Cerveau's novel tau imaging biomarker to study neurofibrillary tangles

Press releases may be edited for formatting or style | January 12, 2023 Molecular Imaging
January 10, 2023 BOSTON--(BUSINESS WIRE)--Cerveau Technologies, Inc. today announced a research collaboration agreement with Othair Prothena Limited, a subsidiary of Prothena Corporation plc (Prothena), which will enable Prothena to use Cerveau’s [F-18]MK-6240, an investigational imaging agent, in Positron Emission Tomography (PET) scans to assess the status and progression of neurofibrillary tangles (NFTs) in the brain. NFTs made up of aggregated tau protein are a hallmark of several neurodegenerative diseases, including Alzheimer’s disease.

The collaboration is focused on using [F-18]MK-6240 as a biomarker in Prothena’s neurodegenerative disease drug research and development. The companies will apply [F-18]MK-6240 imaging to evaluate Prothena’s investigational therapeutics for potential treatment of neurodegenerative diseases in humans, with a focus on Alzheimer’s Disease.

“Cerveau is focused on enabling acceleration of technologies that have the potential to advance the fight against debilitating neurodegenerative diseases,” said Rick Hiatt, Chief Executive Officer, Cerveau Technologies, Inc. “We are excited to add Prothena to our growing network of pharmaceutical partners and global validated production sites. Our goal is to expand the availability of this novel investigational imaging agent to the broader scientific community.”
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About Cerveau Technologies, Inc.
Cerveau’s vision is globally develop diagnostics and technology that positively impact patients with neurodegenerative disorders including Alzheimer’s disease.

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