Postoperatively, the protocol allowed evaluation of surgical success and was helpful in assessing the lungs after lung or stem cell transplant procedures. It may also be useful in follow-up of chronic obstructive pulmonary disease and looking at pathological findings in the lung tissue.
“We believe that the proposed protocol is generally valuable for diseases with known or unknown lung function impairment,” Dr. Shin said.
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Dr. Shin and colleagues first applied the protocol to patients with interstitial lung disease, a group of diseases that cause progressive scarring of the lung tissue. They then expanded the applications to include post-COVID-19 condition where interstitial lung disease sometimes develops.
“With the proposed protocol, we have also been able to answer many other questions related to post-COVID-19 condition, such as the detection of acute and chronic pulmonary emboli on CT angiography, and we are currently investigating whether perfusion changes can be quantified in microvascular damage or inflammatory areas,” Dr. Shin said.
The researchers are working to improve processing time and increase the robustness of the technique.
“Regional ventilation and perfusion depend on patient position and gravity, among other factors,” Dr. Shin said. “Further studies are needed to assess the dependence on position and depth of breathing, as well as the reproducibility of the measurements.”
“Regional Pulmonary Morphology and Function: Photon-counting CT Assessment.” Collaborating with Dr. Shin were Sarah C. Scharm, M.D., Cornelia Schaefer-Prokop, M.D., Hinrich B. Winther, M.D., Carolin Huisinga, M.D., Thomas Werncke, M.D., Jens Vogel-Claussen, M.D., and Frank K. Wacker, M.D.
In 2023, Radiology is celebrating its 100th anniversary with 12 centennial issues, highlighting Radiology’s legacy of publishing exceptional and practical science to improve patient care.
Radiology is edited by Linda Moy, M.D., New York University, New York, N.Y., and owned and published by the Radiological Society of North America, Inc.
About RSNA
RSNA is an association of radiologists, radiation oncologists, medical physicists and related scientists promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Illinois.
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