by
Gus Iversen, Editor in Chief | September 09, 2025
Siemens Healthineers is showcasing an integrated imaging and navigation solution at this year’s World Conference on Lung Cancer (WCLC) in Barcelona, with clinical results suggesting significant improvements in early-stage lung cancer detection.
The system combines Intuitive’s Ion robotic-assisted bronchoscopy platform with Siemens Healthineers’ mobile C-arm, Cios Spin. The latter uses cone beam CT (CBCT) to generate intraoperative 3D imaging, enabling more accurate lesion targeting during biopsy procedures.
According to data presented by the University Hospital of Zurich, one of the first European centers to adopt the solution, the combined platform led to a 291% increase in stage 1A lung cancer diagnoses and a 69% overall increase in lung cancer detections. The diagnostic yield was reported at 89%, including in small, peripheral nodules with a median size of 10 mm and no visible airway path. The system achieved a 99% accuracy rate in tool-in-lesion placement.
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“This technology provides access to very small peripheral lesions that are not directly connected to an airway with unprecedented minimally invasive precision,” said Dr. Carolin Steinack, head of the Interventional Lung Centre in Zurich. “This advantage broadens the spectrum of patients who can benefit from an early, potentially curative diagnosis.”
Lung cancer remains the leading cause of cancer-related death globally. Outcomes improve markedly with early detection: the five-year survival rate is around 84% for patients diagnosed at stage 1A, compared to as low as 4% in late-stage disease.
Operational metrics also improved with use of the combined system. After the learning phase, fluoroscopy time was reduced by 28%, radiation dose by 26%, and the number of CBCT spins by 12%. Procedure times remained comparable to conventional bronchoscopy, averaging 37 minutes.
Dr. Thomas Gaisl, consulting medical director of the pulmonology department at the University Hospital of Zurich, said, “Since the introduction of this integrated solution, we have observed a significant increase in early-stage diagnoses. This not only improves survival prospects but also optimizes resources and ensures greater safety for patients.”
Siemens Healthineers will present the technology and its clinical outcomes during sessions at WCLC through September 9.
