by
Gus Iversen, Editor in Chief | December 05, 2025
GE HealthCare and Mayo Clinic have launched a joint research initiative aimed at advancing personalized radiation therapy through a new program called GEMINI-RT.
The effort builds on their prior strategic collaboration in radiology, signed in 2023, and seeks to integrate imaging, artificial intelligence, and patient monitoring into a more streamlined approach to cancer treatment.
The GEMINI-RT initiative (short for GE HealthCare–Mayo Clinic Initiative in Radiation Therapy) focuses on four core areas: automation, predictive oncology, multimodal therapies, and outpatient monitoring. The goal is to improve treatment accuracy, reduce clinician workload, and expand the role of data-driven decision-making in radiation oncology.
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The companies point to the fact that radiation therapy is used in more than half of all cancer cases and administered to over 2 million patients annually in the U.S. alone. The collaboration will target opportunities to enhance radiation therapy by combining GE HealthCare’s engineering capabilities with Mayo Clinic’s clinical expertise and patient outcomes data.
“GEMINI-RT is grounded in the concept of ‘twinning the patient, personalizing the beam’ — a transformative approach made possible by Mayo Clinic’s extensive clinical expertise and outcomes data,” said Dr. Bryan Traughber, vice chair, innovation for radiation oncology at Mayo Clinic. “The combination of research and technological acumen could allow us to model individual patient journeys with precision, enabling radiation therapy treatments that are truly tailored to each patient.”
The automation effort will explore AI tools to streamline radiation planning by reducing repetitive tasks, while predictive oncology will use data to guide treatment decisions. The initiative will also examine combined-modality therapies, such as pairing radiation with targeted drugs or precision thermal treatments. A fourth component will focus on using wearable sensors, AI, and biomarkers to track patients remotely, aiming to detect side effects early and provide support outside of clinical settings.
