"Unlike cancer biomarkers that focus on static genomic data, our tests based on serum apoptotic DNA tap into the dynamic information provided by the genomic alterations that are unique for each and every cancer cell, thereby capturing what is happening to the DNA very early in the disease process, patient-by-patient and in real time," said Dr. Urnovitz. "These epigenomic signatures captured by the Chronix tests can be used to detect early disease recurrence, and they also can provide information about the disease process to help physicians choose the most appropriate treatment for that patient, making personalized medicine a near-term reality rather than a distant possibility."
Dr. Urnovitz added, "Our 'For Investigational Use Only' testing service is currently making the Chronix technology available to cancer researchers to monitor the status of patients in their clinical trials with a high level of sensitivity and specificity. We are working with these researchers and building partnerships with other oncologists and research institutions to further validate our breast and prostate cancer tests and to generate data on additional cancer indications. We believe that our epigenomic approach based on blood-borne apoptotic DNA has breakthrough potential for the early diagnosis of multiple types of cancer, as well as for helping to improve the effectiveness of cancer treatment. We look forward to working with a variety of collaborators to accelerate its development."
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Commercial applications for veterinary use of the Chronix technology, including tests for the early detection of BSE, or mad cow disease, are in development with the University of Calgary.
The Payor Oncology Management Summit: How Cancer Treatment is Changing & How Payors Should Position Themselves, is being held at the Inner Harbor Marriott Hotel, Baltimore, MD, Nov. 15-16, 2010. For more information, visit http://iibig.com/conferences/P1006/agenda.html.
About Chronix Biomedical
Chronix Biomedical is pioneering a breakthrough approach to the diagnosis, monitoring and management of a broad range of cancers and other conditions. It has developed proprietary technology that measures and categorizes DNA sequences circulating in the blood that are associated with specific changes in disease and health status. Using advanced genome analysis methodology, proprietary data tools and disease-specific databases, Chronix has demonstrated the utility of its diagnostic and prognostic approach in a chronic neurologic disease, in breast and prostate cancer and in multiple myeloma. It is currently conducting studies in other cancers. The company is now offering its Apoptotic Serum DNA testing service to cancer researchers "For Investigational Use Only" to track disease recurrence and monitor treatment in clinical trials. Chronix is headquartered in San Jose, California and has research facilities in Germany. For more information, visit www.chronixbiomedical.com.
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