"The Tissue of Origin Endometrial Test identified specific ovarian and endometrial cancer morphologies even when a clear distinction can be difficult to make by histologic criteria," commented Daniel S. Kapp, M.D., Ph.D., Department of Radiation Oncology, Stanford University, and one of the investigators. "The test can aid in resolving an important differential diagnostic question in gynecologic oncology and may impact clinical management of these patients."
In a third study presented as a poster at ASCO 2012, the relationship between the strength of the Tissue of Origin prediction (known as "Similarity Score") and the subsequent prognosis of tested patients was examined in two observational studies. In both studies, there was a positive relationship observed between the strength of the prediction and the subsequent patient survival.

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The posters, "Retrospective Analysis of Gene Expression Profiling and TTF-1 Staining in Cancer of Unknown Primary (CUP)"; "A Gene Expression Profile Test that Distinguishes Ovarian From Endometrial Cancers"; and "Estimation of Expected Survival Time Using Gene Expression Profiling for Tumor Site Origin" will presented in the Tumor Biology Session of ASCO, Monday, June 4, 1:15-5:15 pm, in S Hall A2.
The most rigorously validated test of its kind, the FDA-cleared Pathwork Tissue of Origin Test is available through the CLIA-certified, CAP-accredited Pathwork Diagnostics Laboratory. The Laboratory also provides the Tissue of Origin Endometrial Test, which is not FDA-cleared. To have a specimen processed by the Pathwork Diagnostics Laboratory or to learn more about the service, call Pathwork Diagnostics at (877) 808-0006 or visit www.pathworkdx.com.
About Pathwork Diagnostics
Pathwork Diagnostics, Inc. is a privately held company based in Redwood City, CA, that
develops and commercializes high-value molecular diagnostics for oncology. The company's
flagship Pathwork Tissue of Origin Test is the only FDA-cleared molecular test of its kind. For more information call toll-free (877) 808-0006 or visit www.pathworkdx.com.
Ed Stevens
727-327-3396
estevens@pathworkdx.com
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